National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
56
2
2013
04
30
Synthesis of New Dipyrimidine and Dialkyl Terephthalate Derivatives from 2,6-Diphenyl-sulphonyloxy-1H, 3H, 5H, 7H-pyrrolo [3,4-F] isoindole- 1, 3, 5, 7-tetrone
111
126
EN
10.21608/ejchem.2013.1102
THE TITLE compound 2 was obtained by treatment of 2,6-dihydroxypyromellitimide 1 with benzenesulphonyl chloride. Compound 2 was used as starting material for the synthesis of new dipyrimidine and dialkyl 2,5-di [(alkoxycarbonyl) amino] terephthalate derivatives. The reaction of 2 with different amines was intensively investigated with respect to the probability of isomerization.
5-Diaminoterephthalic acid diesters,2,6-Dihydroxy-pyromellitic imide,Lossen degradation and Pyrimidinediones
https://ejchem.journals.ekb.eg/article_1102.html
https://ejchem.journals.ekb.eg/article_1102_fad473e2ac0370b050a32c416792ef5c.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
56
2
2013
04
30
Synthesis, Reactions and Characterization of 4,4’-Benzene-1,4-diylbis (5-Acetyl-6-methyl-2-thioxo - 1,2-dihydropyridine-3-carbonitrile)
127
140
EN
10.21608/ejchem.2013.1103
<span style="font-size: xx-small;">BENZENE-1,4-dicarbaldehyde (1) reacted with 2-cyanoethane- …. thioamide (2) to give 3,3'-benzene-1,4-diylbis(2-cyanoprop-2-enethioamide) (3) which in turn, reacted with pentane-2,4-dione (4) to afford the corresponding 4,4’-benzene-1,4-diylbis(5-acetyl-6-methyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile)(5). The synthetic potentiality of compound 5 was investigated in the present study via its reaction with several reagents to afford newly synthesized 4,4’-(1,4-phenylene)-bis (5-acetyl-3-amino-6-methylthieno [2,3-b] pyridines (8a-h). Structures of all newly synthesized heterocyclic compounds in the present study were confirmed by considering the data of IR, </span><span style="font-size: xx-small;">1</span><span style="font-size: xx-small;">H NMR, mass spectra as well as that of elemental analyses </span>
Bis(2-cyanoprop-2-enethioamide),Pentane-2,4-dione,Bis (5-acetyl-6-methyl -2 -thioxo-1,2- dihydropyridine-3 carbonitrile),Bis(5-acetyl-6-methyl-2-alkylthiopyridine-3-carbo-nitrile),and Bis (5-acetyl-3-amino-6-methylthieno [2,3-b] pyridine
https://ejchem.journals.ekb.eg/article_1103.html
https://ejchem.journals.ekb.eg/article_1103_be10e95f38e5f2ecacd989e35ef12985.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
56
2
2013
04
30
Solid Phase Peptide Synthesis of Some Analogs of Bradykinin Hormone Using Microwave Energy Application (part II)
141
153
EN
10.21608/ejchem.2013.1104
<span style="font-size: xx-small;">THREE analogs of Bradykinin, (Cys</span><span style="font-size: xx-small;">6,8</span><span style="font-size: xx-small;">) BK, (Cys</span><span style="font-size: xx-small;">2,5</span><span style="font-size: xx-small;">) BK and (Cys</span><span style="font-size: xx-small;">1,9</span><span style="font-size: xx-small;">) BK were synthesized by modified solid phase peptide synthesis with the application of microwave energy. The effect of the replacement of; Ser</span><span style="font-size: xx-small;">6 </span><span style="font-size: xx-small;">and Phe</span><span style="font-size: xx-small;">8 </span><span style="font-size: xx-small;">by Cys</span><span style="font-size: xx-small;">6,8</span><span style="font-size: xx-small;">, Pro</span><span style="font-size: xx-small;">2 </span><span style="font-size: xx-small;">and Phe</span><span style="font-size: xx-small;">5 </span><span style="font-size: xx-small;">by Cys</span><span style="font-size: xx-small;">2,5</span><span style="font-size: xx-small;">,and Arg</span><span style="font-size: xx-small;">1,9 </span><span style="font-size: xx-small;">by Cys</span><span style="font-size: xx-small;">1,9 </span><span style="font-size: xx-small;">on the biological activity of bradykinin was investigated. A continued work of a previously done study includes synthesis of three BK analogs, (Lys</span><span style="font-size: xx-small;">1</span><span style="font-size: xx-small;">) BK, (Lys</span><span style="font-size: xx-small;">9</span><span style="font-size: xx-small;">) BK and (Lys</span><span style="font-size: xx-small;">1, 9</span><span style="font-size: xx-small;">) BK, using the modified solid phase peptide synthesis with microwave energy. The six analogues have been tested </span><em><span style="font-family: Times New Roman,Times New Roman; font-size: xx-small;"><span style="font-family: Times New Roman,Times New Roman; font-size: xx-small;">in vitro </span></span></em><span style="font-size: xx-small;">for their effect on heart rate and in isolated organ for the arterial pressure of rats. </span>
Bradykinin,Modified solid phase peptide synthesis and Microwave energy
https://ejchem.journals.ekb.eg/article_1104.html
https://ejchem.journals.ekb.eg/article_1104_6ea7a4d837ea59b4c3c17af8fe5fd999.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
56
2
2013
04
30
Physicochemical and Fire Resistance Characteristics of Artificial Pozzolanic Cement Pastes
155
168
EN
10.21608/ejchem.2013.1105
<span style="font-size: xx-small;">THE PRESENT work describes details concerning preparation and ….. physico-chemical characterization of pozzolanic cement pastes . The prepared cement pastes were examined by using XRD, SEM and nitrogen adsorption at-196</span><span style="font-size: xx-small;">o</span><span style="font-size: xx-small;">C. The results revealed that the physicochemical and mechanical properties of the solids investigated could be related to the microstructure and surface properties of the hardened pozzolanic cement pastes. It was found that the pozzolanic cement blend containing 20% Homera has the highest to fire resistance </span>
Ground clay brick,surface,Compressive strength and Fire resistance
https://ejchem.journals.ekb.eg/article_1105.html
https://ejchem.journals.ekb.eg/article_1105_0159f164168cd4247fbf07293cec66dc.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
56
2
2013
04
30
More Insight on Charcterization of Nano-sized Particles of Silver Powder and their Application in Antimicrobial Wound Dressing and Anti-inflammatory Efficacy
169
185
EN
10.21608/ejchem.2013.1106
<span style="font-size: xx-small;">POWDERED silver nanoparticles (AgNPs) was successfully …….prepared.through addition of AgNO</span><span style="font-size: xx-small;">3 </span><span style="font-size: xx-small;">to alkali dissolved starch. The latter was used as eco-friendly biopolymers which played the dual role as reducing and stabilizing agent followed by precipitation with ethyl alcohol. The as prepared AgNPs powders have the smallest size (12-22nm), polydispersity (0.163) as well as zeta potential (-28mv) indicating higher surface area, the highly distributed nanoparticles as well as long-term stability of their product. These powdered AgNPs were re-dispersed in distilled water and diluted to different concentrations (250, 125 and 60 ppm). The diluted solution of AgNPs was applied to cotton fabrics as per the pad-dry-cure technique. The antimicrobial, wound healing, anti-inflammatory as well as toxicity of cotton fabrics loaded with these three different concentrations of AgNPs colloidal solution were evaluated. AgNPs in three different states, viz., in the powder form, in aqueous solution and deposited onto cotton fabrics were characterized using the world-class facilities such as UV-Vis spectroscopy, Transmission Electron Microscopy (TEM), Particle size analyzer, Polydispersity index (PdI), Zeta potential (ZP) and Scanning Electron Microscopy connected with Energy Dispersive X-ray (SEM-EDX). Cotton fabrics containing 250 ppm AgNPs were more effective against different species of microorganisms than those of dressing containing 60 and 125 ppm as indicated by the inhibition zone. Wound healing caused by dressing containing the highest content of AgNPs displayed the highest potent healing, with great similarity to the controlled cream (Dermazin). Moreover, the anti-inflammatory effect of 0.5 ml dose AgNPs (250 ppm) is nearly similar to 20 ml dose of the reference drug (indomethacin). Also reported was that, the Minimum Inhibitory Concentration (MIC) for the produced AgNPs on subsequent experiments was 10 μg/ml. </span>
Silver was extensively used to control infections since ancient times. Nowadays, silver is finding wide- spread applications in medical domains
<strong><span style="font-family: Times New Roman,Times New Roman; font-size: xx-small;"><span style="font-family: Times New Roman,Times New Roman; font-size: xx-small;">(1)</span></span></strong><span style="font-size: small;">. Silver-based medical products were proven to be effective in retarding and preventing bacterial infections</span><strong><span style="font-family: Times New Roman,Times New Roman; font-size: xx-small;"><span style="font-family: Times New Roman,Times New Roman; font-size: xx-small;">(2)</span></span></strong><span style="font-size: small;">. It is worthy reporting that there is an increasing interest toward the exploitation of silver nanoparticles technology in the development of </span>
https://ejchem.journals.ekb.eg/article_1106.html
https://ejchem.journals.ekb.eg/article_1106_148eae93a1cce44bdb15a796b085717a.pdf