National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Preparation, Characterization, In vitro Cell Cytotoxicity and Biological Studies of Pd(II), Ag(I), Pt(IV) and Hg(II) Piroxicam Anti-inflammatory Drug Complexes
4671
4680
EN
Walaa
El-Shwiniy
0000-0002-7577-8090
Department of Chemistry, College of Science, University of Bisha, Bisha, 67714 Kingdom of Saudi Arabia
wh595949@gmail.com
Mostafa Y.
Nassar
Department of Chemistry, Faculty of Science, Benha University, Benha 13518, Egypt
A.M.A.
Shehata
Department of Chemistry, College of Science, University of Bisha, Bisha, 67714 Kingdom of Saudi Arabia
S. I.
El-Desoky
Department of Chemistry, Faculty of Science, Benha University, Benha 13518, Egypt
10.21608/ejchem.2019.16596.2011
Novel Pd(II), Ag(I), Pt(IV) and Hg(II) piroxicam (Pir) anti-inflammatory drug complexes were obtained upon the reaction of metal salts with piroxicam (Pir) in ethanol solvent at 60 °C. The proposed structure was explained with the aid of microanalytical analyses, conductivity, spectroscopic (FT-IR and UV-Vis.), magnetic calculations and thermogravimetric analyses (TG/TGA). The ratio of metal: Pir drug is found to be 1:2 in all complexes estimated by using molar ratio method. The conductance data reveal that Pd(II), Pt(II) and Hg(II) chelates are non-electrolytes except Ag(I) complex. The infrared spectrum of free piroxicam in comparison with its chelates indicated that the chelation mode occurs via the oxygen and nitrogen atoms of ν(C=O)carbonyl and ν(C=N)pyridyl, respectively. The kinetic parameters of thermogravimetric and its differential, such as activation energy, entropy of activation, enthalpy of activation, and Gibbs free energy were evaluated using Coats-Redfern and Horowitz-Metzger equations for Pir drug and its complexes. The antimicrobial tests were assessed toward some types of bacteria and fungi. The in-vitro cell cytotoxicity of the complexes in comparison with Pir against colon carcinoma (HCT-116) cell line was investigated
Piroxicam (Pir),IR spectroscopy,Thermal analysis,Cytotoxicity
https://ejchem.journals.ekb.eg/article_101434.html
https://ejchem.journals.ekb.eg/article_101434_5d5dc2cbd617943a402cb6b8dd05c6f4.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Spectrophotometric Determination of Paracetamol using a Newly Synthesized Chromogenic Reagent 4-[(2-amino-1, 3thiazol-4-yl)amino]nitro benzene
4681
4693
EN
Ruba
F.
Abbas
0000-0003-4865-5658
Department of Chemistry, College of Science-University of AL-Mustansiriyah- Baghdad-Iraq
suha_rrr_1983@yahoo.com
Amjad
G
Allawi
chemistry department, collage of science, al mustansiriyah university
a_amjadd@uomustansiriyah.edu.iq
Nagham
M
Abdulhassan
chemistry department, collage of science, al mustansiriyah university
naghammejed217@gmail.com
Nawal
H
Mahmoud
chemistry department, collage of science, al mustansiriyah unversity
nawlives7@yahoo.com
10.21608/ejchem.2020.17136.2053
This study describes the new simple and accurate spectrophotometric method for the determination of paracetamol after the formation of azo dye with a new chromogenic reagent 4 [(2-amino-1,3thiazol-4-yl)amino] nitrobenzene to form an orange-coloured product measured at 425 nm. The molecular structure of the newly synthesized compound was confirmed by several spectroscopic techniques such as UV-visible, FTIR, 1HNMR, and mass spectroscopy. Newly synthesized compound was in vitro screened against several bacterial species. The experimental conditions that affect the reaction were carefully optimized and under the optimized conditions, a linear relationship was obtained in the concentration range of 5–25mg.L−1 of paracetamol. A reaction with a new chromogenic reagent has been occurred at a stoichiometric ratio of 1:1. This method has a limit of detection of 1.334 mg.L-1 and Sandell's sensitivity of 0.0235 mg.cm-1 for new azo dye product.
Paracetamol,azo dye,Antibacterial activity,Thiazol,IHNMR,Spectrophotometric
https://ejchem.journals.ekb.eg/article_94126.html
https://ejchem.journals.ekb.eg/article_94126_d6ccd74695427edb2cc9527ca6ef8d8f.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
The efficiency of bank filtration to remove chemical pollutants in Egypt: field and batch studies
4695
4701
EN
A.
Abogabal
Holding Company for Water and Wastewater, Cairo, Egypt.
abogabal_chem@yahoo.com
K.
Khodeif
Geology Department, Faculty of Science, Suez Canal University, Egypt.
kghodeif@yahoo.com
M. B.M.
Ibrahim
Holding Company for Water and Wastewater, Cairo, Egypt.
mohamed.bakr@hcww.com.eg
E.
Souya
Chemistry Department, Faculty of Science, Ain Shams University, Egypt
eglals@yahoo.com
10.21608/ejchem.2020.17965.2093
Bank filtration (BF) is a low-cost water treatment technology in which surface water contaminants are removed through the biochemical and physical process taking place during the filtration process. This study aimed to assess the effectiveness of this technique to produce high drinking water quality in Egypt. In this study, field-works was conducted, and samples were collected from the River Nile and the bank filtrate wells at Sultana Town, El Menyia Governorate. The samples were analyzed and the chemical pollutants (e.g., pesticides, pharmaceuticals, inorganic) were determined. Moreover, batch studies were conducted to get insight on the mechanical removal of the organic contaminants and to assess the impact of temperature (15, 25, 30 ºC) and redox condition ( oxic, anoxic) conditions on the removal. The results revealed that bank filtration can remove the inorganic pollutants such as ammonia and nitrate efficiently. However, its effectiveness to remove organic pollutants is highly dependent on the temperature; higher removal was obtained at a higher temperature. To conclude, bank filtration is an effective technique to remove chemical contaminants and to produce high water quality, and it is highly recommended to extend the usage of this technique in Egypt.
bank filtration,Egypt,organic and inorganic pollutants
https://ejchem.journals.ekb.eg/article_78945.html
https://ejchem.journals.ekb.eg/article_78945_733355b9d05bd527e005a5dc3a8edc22.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Density Functional Theory (DFT) Investigation and Molecular Docking Simulation of 1, 2, 4-triazole Derivatives as Potent Inhibitors Against a Receptor (DNA Gyrase)
4703
4717
EN
SHOLA
ELIJAH ADENIJI
0000-0002-7750-8174
BAYERO UNIVERSITY KANO
shola4343@gmail.com
10.21608/ejchem.2020.21024.2253
Abstract<br /> Time consumed and expenses in discovering and synthesizing new hypothetical drugs with improved biological activity have been a major challenge toward the treatment of multi-drug resistance strain Mycobacterium tuberculosis (TB). To solve the above problem, Quantitative structure activity relationship (QSAR) is a recent approach developed to discover a novel drug with a better biological against M. Tuberculosis. The developed model was validated through internal and external validation test. Molecular docking studies was as well carried for all the studied compounds in order to show the interactions and binding modes between the ligand and the receptor (DNA gyrase). The lead compound (compound 3) with higher anti-tubercular activity was observed with prominent binding affinity of -11.8 kcal/mol. Therefore, compound 3 could serve as a template structure to designed compounds with more efficient activities. The outcome of this research is recommended for pharmaceutical and medicinal chemists to design and synthesis more potent compounds with prominent anti-tubercular activities using the model designed in this study.
Keywords: Anti-tuberculosis,binding affinity,DNA Gyrase,Molecular docking,QSAR
https://ejchem.journals.ekb.eg/article_98022.html
https://ejchem.journals.ekb.eg/article_98022_0678baae05a71e6934a28b724f21760a.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Synthesis, Characterization, Industrial And Biological Application Of Co(II),Ni(II),Cu(II) And Zn(II) Complexes With Azo Ligand Derived From Metoclopramide Hydrochloride And 3,5-Dimethylphenol
4719
4729
EN
Shatha
M H
obaid
Department of Chemistry, College of Education for Pure Science /Ibn-Al-Haitham, University of Baghdad
shathaobaid@yahoo.com
Afnan
E
Abd-Almonuim
Pharmacy Department, Al-Rasheed University College/ Baghdad-Iraq
afnan.abdalmonuim@gmail.com
amer
J
jarad
Department of Chemistry, College of Education for Pure Science (Ibn Al-Haitham), University of Baghdad, Baghdad, Iraq
amerjj2006@yahoo.com
10.21608/ejchem.2020.21400.2283
Four complexes of Co(II),Ni(II),Cu(II) and Zn(II) with the azo ligand (4-chloro-N-(2-(dimethylamino)ethyl)-5-((2-hydroxy-4,6-dimethylphenol)diazenyl)-2-methoxybenzamide) L. The structure of ligand and complexes were confirmed on the basis of their analytical and spectral data, these dyes were tested as dyeing in cotton fabric, and also testing in light and cleaner firmness. Also, antimicrobial and antifungal activities of ligand and their complexes were evaluated and the results showed that the ZnL compound showed the higher antibacterial activity with inhibition zone of 13mm against Staphyloco-ccus epidermidis, Steptococcus sp. and Escherichia coli compared with ligand and other metal complexes .In case of ZnL compound the antifungal activity of Candida albicans showed higher inhibition area of 15mm is higher activity from ligand and rest metal complexes. , there is no doubt, that the effort exerted by the scholar was good enough. But I found a few point must corrected.
metoclopramide,Azo dyes,dyeing,3,5-dimethylphenol
https://ejchem.journals.ekb.eg/article_103746.html
https://ejchem.journals.ekb.eg/article_103746_d1ff7732130ebb368f3645fed8a752ba.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Adsorption Isotherms and Thermodynamic Study of Direct Blue2 (DB2) Dye on Y2O3 Nanoparticles
4731
4737
EN
Athraa
S.
Ahmed
department of chemistry, college of science, al-mustansiriyah university, iraq
athraa.salman@yahoo.com
Barakat
A. F.
Kamel
0000-0002-9601-0849
department of chemistry, college of science, al-mustansiriyah university, iraq
baraka19832012@yahoo.com
Shaimaa
H.
Jaber
department of chemistry, college of science, al-mustansiriyah university, iraq
shaemaahamed@yahoo.com
10.21608/ejchem.2020.22123.2340
In this work, the adsorption of DB2 dye on yttrium oxide (Y2O3) nanoparticles was investigated under various experimental conditions. The effect of temperatures and pH were studied, it was noted that the increasing in temperatures increases the adsorption quantity, which is increased in icidic medium and decreased in basic medium. The isotherm models ( Langmiur, Freundlich, Temkin, Halsey and Harkins-Jura) were applicated and the isotherms can be arrange according to its high correlation-coefficients as follows: Freundlich (0.969) > Harkins-Jura (0.957) > Halsey (0.944) > Temkin (0.942) > Langmiur (0.902), the Freundlich isotherm model is suitable for the adsorption process. Thermodynamic Parameters such as ΔH, ΔG and ΔS were calculated from the slops and intercepts of the linear variation of lnk against 1/T, where noted that the adsorption of DB2 dye on Y2O3 nanoparticles is ( endothermic reaction)
adsorption isotherms,DB2 Dye,Y2O3 Nanoparticles
https://ejchem.journals.ekb.eg/article_94128.html
https://ejchem.journals.ekb.eg/article_94128_0d2d2b05c5b0b2924b505df0df779b0f.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Effect Of Gamma Irradiation and Tannic Acid On The Chemical And Physical Properties Of Poly(Vinyl Alcohol)/Wheat Gluten (Pva/Wg) Polymer Blends
4739
4747
EN
Salwa
Khalil
Radiation Chemistry Department, National Center for Radiation Research and Technology, Nasr City, Cairo, Egypt
salwancrrt@yahoo.com
Nashwa
Shoaib
Chemistry Department, Faculty of Science, Menoufia University
nashwashoaib89@gmail.com
Yasser
Kamal
Abdel-Monem
0000-0002-7032-5519
Chemistry department, Faculty of science, Menoufia university
ykabdelmonem@science.menofia.edu.eg
Magdy
Senna
https://orcid.org/00
Radiation Chemistry Department, National Center for Radiation Research and Technology, Nasr City, Cairo, Egypt
magdysenna@hotmail.com
10.21608/ejchem.2020.22565.2342
Films of poly(vinyl alcohol)/wheat gluten (PVA/WG) polymer blends at different compositions were prepared by solution casting and then exposed to a constant dose of gamma irradiation. In addition, the PVA/WG polymer blends were modified by adding a constant ratio (4%) of tannic acid (TA) to the casting solution. The PVA/WG polymer blends before and after gamma irradiation as well as those modified by tannic acid were characterized by Fourier transform infrared (FTIR) spectroscopic analysis, thermogravimetric analysis (TGA), scanning electron microscopy (SEM) and measuring the tensile mechanical properties. The antimicrobial activity of PVA/WG polymer blends was also investigated. FTIR spectroscopic analysis indicated that a hydrogen bond was formed between TA and PVA also irradiation improves the adhesion between PVA and WG this conclusion also supported by scanning electron microscopy (SEM) and measuring the tensile mechanical properties. The antimicrobial properties indicated that irradiated sample was better than unirradiated samples.
Poly(vinyl alcohol,Wheat gluten,Gamma Irradiation,tannic acid,Tensile Properties,Thermal properties
https://ejchem.journals.ekb.eg/article_95789.html
https://ejchem.journals.ekb.eg/article_95789_92ee6887889097ef4bdf51fc1502e32f.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Synthesis , Spectral Characterization And Anticancer Studies of Novel Azo Schiff Base And its Complexes with Ag(I),Au(lll) And Pt(lV) ions
4749
4756
EN
shaimaa
adnan
university of Al-Qadisiyah
shemaadnan@yahoo.com
Khalid
J- Al-Adilee
college of Education , university of Al-Qadisiyah
khalidke-1962@yahoo.com
Khamis
A-Abedalrazaq
Universty of Al-Anbar
khalid.jawad@qu.edu.iq
10.21608/ejchem.2020.23312.2438
A novel azo schiff base dye (L) has been Synthesized a reaction of 5- [ 2-(5-nitro thiazolyl)azo] -2-amino -4-methyl pyridine (NTAPy) with 4-chloro benzaldehyde in alkaline solution . Anew series of complexes with Ag(I) ,Au(III) and Pt(IV) ions was Prepared forming chelate complexes . The structure of azo schiff base ligand and its metal complexes were characterized by different spectral technique such as1H-NMR, 13C-NMR, mass spectrum , FT-IR, electronic Spectra , C-H.N.S analysis , magnetic susceptibility ,atomic absorption and molar conductivity .The analytical data suggests the mole ratio [ M:L] was [l:l] for Ag(I)and Au(III) ions but [l:2] for Pt(IV) ion. The metal complexes of Au(III) and pt (IV) was l:l and l:2 electrolyte receptivity while the Ag(I) complex is non electrolyte . In this study the cytoxicity of Ag(I), Au(III), and Pt (IV) complexes on humn (PC3) breast cancer and normal cells were MTT assay .
Azo,Schiff base,metal complexes and anticancer (breast cancer)
https://ejchem.journals.ekb.eg/article_91905.html
https://ejchem.journals.ekb.eg/article_91905_29a91a6bc4bd653fca91b5a34f931dad.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Synthesis and characterization of novel mixed complexes derived from 2-aminomethylbenzimidazole and 2-(1H-Benzimidazol-2-yl) aniline and theoretical prediction of toxicity
4757
4767
EN
aroua
lotfi
Department of Chemistry, College of Science, Qassim University, Campus University, King Abdulaziz Road, Al-Malida, 51452 - P.O.Box:
6644, Buraydah, Qassim, Kingdom Saudi Arabia.
aroua.lotfi@yahoo.com
10.21608/ejchem.2020.24418.2453
Abstract: Novel complex derived from 2-aminomethylbenzimidazole, 2-(1H-benzimidazol-2-yl) aniline and metal chloride (Cd (II), Ni(II) and Cu(II)) was successfully synthesized. All newly complexes were fully characterized by spectroscopic data of FT-IR, UV-Visible electronic absorption, X-ray powder diffraction, and thermal analysis. IR spectra of the metal complexes revealed the coordination of the ligands to the metal ions via nitrogen atoms and mass spectra proposed that have a tetrahedral structure. The X-ray powder diffraction results affirmed that the Cu (II) complex has a triclinic structure, Cd (II) complex possess a triclinic structure and Ni (II) complex occupy a rhombohedral structure. The bioactivity score of tested compounds possesses a similar as compared to aspirin for all drug targets. The results of the theoretical toxicity study of different new complexes have been achieved based on program protox-II-prediction toxicity of chemicals and revealed that all target compounds exhibited no significant toxicity to all human cells.
Keywords: Mixed complex,2-aminomethylbenzimidazole,2-benzimidazole aniline,Spectral studies,XRD analysis,Thermal stability,theoretical prediction of toxicity
https://ejchem.journals.ekb.eg/article_91906.html
https://ejchem.journals.ekb.eg/article_91906_60ba4b10cf54724850a5d358dcf7f9c2.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Synthesis Biological Studies of Some New Heterocyclic Compound Derived From 2-Chloro-3-Formyl Quinoline And 4-(Benzyl Sulfonyl) Acetophenone
4769
4776
EN
Mohanad
Saleh
0000-0003-2320-5167
Department of Chemistry, College of Education for pure science, University of Mosul
mohanadalallaf@uomosul.edu.iq
Ala
I
Ayoub
Department of Renewable Energies , college of Sciences, University of Mosul
allaaa1959@yahoo.com
Ali
O.
Hammady
Remote sensing and Gls , college of Sciences, University of Baghdad
ali.o@se.uobaghdad.edu.iq
10.21608/ejchem.2020.26354.2535
A new series of quinoline chalcones have been prepared from condensations of 2-chloro-3-formyl quinoline (1) with 4-(benzothio) acetophenone(2) and 4-(benzyl sulfonyl) acetophenone(3). The reaction of chalcones(4,5) with bromine gives dibromide(6,7). New pyrazoline derivatives were synthesized by condensation of chalcones (4 or 5) with hydrazine hydrate to give (8,9) and with hydrazine hydrate in glacial acetic acid(gla) to give (10,11) and with phenyl hydrazine to give (12,13). The prepared chalcones (4,5) and dibromide(6,7) and pyrazoline derivative (8-13)have been screened for anti-bacterial activities against two gram positive staphylococcus aureus and staphylococcus epidermidis and two gram negative Escherichia coli and Proteus vulgaris. The synthesized compounds are proven by IR & NMR spectral and physical method.
2-chloro-3-formyl quinoline,Chalcones,Dibromide,4-(benzyl sulfonyl) acetophenone,4-(benzothio) acetophenone
https://ejchem.journals.ekb.eg/article_94129.html
https://ejchem.journals.ekb.eg/article_94129_13d191463a9c48d9ca4386bd8401a877.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Molecular Modeling Applied For Carbon Nano Materials
4777
4787
EN
Hend
Ezzat
Nano Lab, National Research Institute of Astronomy and Geophysics (Nano NRIAG), Helwan, Cairo,
hend_ahmed16@yahoo.com
Medhat
Ibrahim
0000-0002-9698-0837
medahmed6@yahoo.com
Hanan
Elhaes
Physics department, Ain shams university
medahmed@yahoo.com
10.21608/ejchem.2020.26861.2551
Molecular modeling is applying computer software to describe the molecular systems. This leads to understating many systems and structures in chemical, biological systems. Molecular modeling is now widely used in much basic as well as applied science. On the other hand, carbonaceous materials which also known as carbon nano materials have attracted interests of many researchers according to their amazing special structures and extraordinary electronic properties. So that, research on the carbon nano materials are now increasing rapidly. Accordingly, carbon nano materials are surveyed with special care to fullerene, carbon nanotubes and graphene as well as their based systems. The review include how can molecular modelling describe the physical, chemical and functionality of the carbon nano materials. The review includes the following points<br /> Introduction<br /> Molecular modeling<br /> Calculated parameters through molecular modeling<br /> Carbon nano materials <br /> Fullerene based systems <br /> CNT based systems <br /> Graphene based systems <br /> Modeling other forms of carbon<br /> Conclusion and outlook
Molecular modeling,fullerene,CNT,Graphene
https://ejchem.journals.ekb.eg/article_102655.html
https://ejchem.journals.ekb.eg/article_102655_3cc87370b47c189896f727c3e4aa7e14.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Modeling the Effect of Zinc Oxide on the Electronic Properties of Polyvinyl Alcohol
4789
4796
EN
Rania
Badry
Physics Department, Faculty of Women for Arts, Science and Education, Ain Shams University, 11757 Cairo,
Egypt
Asmaa
Ibrahim
Basic Science Department, October High Institute for Engineering & Technology, Misr University for Science
and Technology, 6th October City, Cairo, Egypt.
Fatma
Gamal
Physics Department, Faculty of Women for Arts, Science and Education, Ain Shams University, 11757 Cairo,
Egypt
Samah A.
Ibrahim
Physics Department, Faculty of Science, Ain Shams University, 11566 Cairo, Egypt.
Hend
Ezzat
Nano Lab, National Research Institute of Astronomy and Geophysics (Nano NRIAG), Helwan, Cairo, Egypt
hend_ahmed16@yahoo.com
Hanan
Elhaesa
Physics Department, Faculty of Women for Arts, Science and Education, Ain Shams University, 11757 Cairo,
Egypt
Medhat
Ibrahim
0000-0002-9698-0837
Molecular Spectroscopy and Modeling Unit, Spectroscopy Department, National Research Centre, 33 El-
Bohouth St., 12622, Dokki, Giza, Egypt
medahmed6@yahoo.com
10.21608/ejchem.2020.27245.2564
A compactional study for the physical properties of polyvinyl alcohol PVA in its emeraldine base form (4PVA) was presented. Both PM6 semiempirical and DFT:B3LYP/LANL2DZ levels are conducted to elucidate the ZnO effects on the electronic and surface properties of PVA. The influence of ZnO was introduced in terms of total dipole moment (TDM), HOMO/LUMO band gap energy (ΔE) and molecular electrostatic potential (MESP). The results indicated that, TDM of 4PVA and the band gap energy were changed by changing the interaction site. Where, the band gap energy of 4PVA decreased sharply with ZnO addition and the electron density together with the reactivity was increased as presented in MESP maps. Also, the influence of ZnO addition was clearly observed from TDM and band gap energy values calculated with DFT than that at the PM6 level. The difference between both methods could be attributed to electron correlation which is included in DFT rather than PM6, this makes DFT more accurate than PM6.
4PVA,ZnO,Electronic properties,Semi-empirical methods and DFT: B3LYP/LANL2DZ
https://ejchem.journals.ekb.eg/article_102656.html
https://ejchem.journals.ekb.eg/article_102656_d40c0178bce962e47a2722d7242c0c7d.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Synthesis and Docking Studies of a Novel Tetrahydroquinazoline Derivative as Promising Scaffold for Acetylcholine Esterase Inhibition
4797
4804
EN
Rawan
A.
Alsuhaimat
Faculty of Pharmacy, Mu’tah University, Al-Karak, 61166, Amman, Jordan
alsuhaimatr@gmail.com
Qais
Abualassal
Department of Applied Pharmaceutical Sciences, Faculty of Pharmacy, Isra University, Amman, Jordan
qais.abualasal@iu.edu.jo
zead
abudyah
Faculty of pharmacy / AL-isra university
Amman / Jordan
zead.helmi@outlook.com
Sherif
S.
Ebada
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Mu’tah University, Al-Karak, Jordan. and Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo, Egypt
sherif_elsayed@pharma.asu.edu.eg
Amgad
Albohy
0000-0003-3021-8767
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, The British University in Egypt (BUE), Egypt
albohy@ualberta.ca
10.21608/ejchem.2020.27985.2588
Alzheimer’s disease (AD) is one of the most prevalent neurodegenerative disorder. While pathological hallmarks of this disorder are known, the exact cause of AD remains unclear. Quinazoline was found to be a promising scaffold for the design and development of Acetylcholinesterase (AChE) inhibitors. In this study we report the synthesis of 1'-methyl-3', 4'-dihydro1'H-spiro[cyclopentane-1, 2'-quinazoline] (4) in 73.3% yield. The structure of compound 4 was confirmed with GC-MS, 1H and 13C-NMR. Acetylcholine esterase inhibition was studied virtually with docking into AChE active site and suggests potential use of 4 as a promising scaffold for acetylcholine esterase inhibitor design which might be useful for Alzheimer’s disease.
Acetylcholine esterase inhibitor,Alzheimer disease,Quinazoline derivatives,Spiro compounds,Molecular docking
https://ejchem.journals.ekb.eg/article_96061.html
https://ejchem.journals.ekb.eg/article_96061_fc0c0efa03b7bb42401aec6abf3b1a7f.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Treatment of petroleum refinery wastewater by electro-Fenton process using porous graphite electrodes
4805
4819
EN
Ahmad
S.
Fahim
0000-0001-5423-2884
Department of Chemical Engineering, College of Engineering, University of Al-Qadisiyah , AL-Qadisiyah, Iraq
ahmedsalah19994@gmail.com
Ali
H.
Abbar
Department of Chemical Engineering, College of Engineering, University of Al-Qadisiyah , AL-Qadisiyah, Iraq
ali.abbar@kecbu.uobaghdad.edu.iq
10.21608/ejchem.2020.28148.2592
The present paper deals with the treatment of wastewaters generated from Al-Dewaniya petroleum refinery plant by Electro-Fenton process in a batch electrochemical reactor using porous graphite as anode and cathode materials. Effects of operating factors such as current density (5-25mA/cm2), FeSO4 concentration (0.1-0.7mM), NaCl addition (0-2g/l), and time (15–45min) on the efficiency of the chemical oxygen demand (COD) removal were studied. The results revealed that FeSO4 concentration has the main effect on the efficiency of COD removal confirming that the Electro-Fenton process was governed by reaction conditions in the bulk of solution between ferrous ions and H2O2 not upon the electrochemical reactions on the surface of electrodes. Parametric optimization was carried out using response surface methodology (RSM) combined with Box–Behnken Design (BBD) to maximize the removal of COD. Under optimized operating conditions: FeSO4 concentration (0.7mM), current density (25 A/cm2), and time (45 min) with no addition of NaCl, the removal efficiency of COD was found to be 95.9% with an energy consumption of 8.921kWh/kgCOD.
petroleum refinery wastewater,Electro-Fenton process,porous graphite,Response surface methodology,COD removal
https://ejchem.journals.ekb.eg/article_94132.html
https://ejchem.journals.ekb.eg/article_94132_ea8dd4c71b88a577d37d6b9594ab8b0d.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Mechanical Properties, Resistance to Fire and Durability for Sulfate Ions of Alkali activated Cement made from Blast furnace Slag- Fine Metakaolin
4821
4831
EN
Osama
Fadel
Sakr
Physical Chemistry and Building Materials, Faculty of Science, Ain Shams University
chemist.osama.fadel@gmail.com
Eisa
El-Sayed
Hekal
Physical Chemistry and Building Materials, Faculty of Science, Ain Shams University, Cairo, Egypt
eisa_hekal@yahoo.com
Fayza
Hashem
0000-0003-0027-8654
Abdel shafei Mhmed
Ain shams university
f_s_hashem@ymail.com
Faten
Rayan
Selim
Physical Chemistry and Building Materials, Faculty of Science, Ain Shams University, Cairo, Egypt
faten_chem@yahoo.com
10.21608/ejchem.2020.28427.2612
The characterization of alkali activated cement prepared by blending blast furnace slag (BFS) and fine metakaolin (FMK) are studied. MK of particle size 45 μm and blain area 6530 cm2/kg is used as 20%, 40%, 60% and 80% replacement of BFS in the production of alkali activated cement. The alkaline activator used was mixture of NaOH and Na2SiO3 with various molar ratios. The prepared specimens are cured under humid conditions up to 90 days. All specimens are characterized regarding setting times, compressive strength and water absorption. The formed hydrates are studied using XRD analysis, FTIR spectroscopy and SEM. The durability of the prepared geopolymer are determined via studying the fire resistance at 300 o, 600 o and 800 oC and sulfate ions attacks after time intervals extended up to 1 year. The results indicate that the specimens made from 60% BFS and 40% FMK and activated by (1:1) NaOH and Na2SiO3 were revealed the best overall behavior.
Geopolymer,Slag,Metakaolin,Thermal resistance,Sulfate resistance
https://ejchem.journals.ekb.eg/article_91907.html
https://ejchem.journals.ekb.eg/article_91907_736e37f0f267f0e22cc4d7312cb90434.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Synthesis, characterization and in-vitro antimicrobial evaluation of thermally and photostable Schiff base-modified PVC/nanocomposites
4833
4849
EN
dina
Ali
national research centre
dinarayan2007@gmail.com
Nahid
Khaireldin
NRC
nahid_khaireldin@hotmail.com
Maher
El-Hashash
Chemistry Department, Faculty of Science
Ain Shams University
Cairo 11566, Egypt
maeelhashash@yahoo.com
manal
elsaidi
nrc
elsaidi@hotmail.com
Ahmed
A.
El-Sayed
0000-0003-2555-5259
Photochemistry Department, Industrial Research Division, national research Centre, Dokki, Cairo, Egypt
ahmedcheme4@yahoo.com
Nayera A.M.
Abdelwahed
nrc
niarawahed@yahoo.com
samira
taha
rabie
national research centre
str_strabie@yahoo.com
10.21608/ejchem.2020.28830.2618
Two Schiff base derivatives, 4-[(2, 5-dimethoxy phenylimino)-methyl] phenol, SB1 and 4-[(2-hydroxy benzylidine)-amino] phenol SB2, have been prepared and used as modifiers for polyvinyl chloride (PVC). Chemical modification of PVC was performed using these Schiff bases in presence of AgNO3 to obtain two modified PVC nanocomposite, PVC-SB1/AgNPs and PVC-SB2/AgNPs, and their chemical structures were confirmed by FTIR, 1H-NMR, 13C NMR and Mass spectroscopy. Scanning and transmission electron microscopy were performed for the modified polymer nanocomposites. The SEM and TEM micrographs of PVC-SB/AgNPs showed homogeneous surface polymeric matrix with uniform distribution of AgNPs, and their diameters are in the nanoscale. Moreover, thermal and photostabilities as well as mechanical properties of the modified polymer nanocomposites were also investigated. Moreover, mechanical properties of PVC-SB/AgNPs were also investigated. Antimicrobial activity of the modified PVC was evaluated against two Gram +ve bacteria (Bacillus subtilis and Staphylococcus aureus) and two Gram -ve bacteria (Escherichia coli and Pseudomonas aeruginosa) as well as Candida albicans as fungus.
Modified PVC,Schiff base,photostability,antimicrobial activity
https://ejchem.journals.ekb.eg/article_97552.html
https://ejchem.journals.ekb.eg/article_97552_0196ef478017383535ffa1492da77fee.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Quinazolinone-Schiff's Base hybrids as Phosphodiesterase 4B inhibitors with dual activity against COPD and Lung Cancer
4851
4866
EN
Mostafa
Mansour
0000-0002-0179-8398
Pharmaceutical Chemistry Department, Faculty of Pharmacy, Nahda University, Beni-Suef, Egypt
mostafa.mansour@nub.edu.eg
Mohammed
T
El-Saadi
Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt
Medicinal Chemistry Department, Faculty of Pharmacy, Sinai University, Ismailia, Egypt.
moh1_ttaha@yahoo.com
Noha
H
Amin
Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt
hani.noha@gmail.com
Joshua
Canzoneri
USA Mitchell Cancer Institute Drug Discovery Laboratory, University of South Alabama, USA.
jcanzoneri@health.southalabama.edu
Adam
Keeton
USA Mitchell Cancer Institute Drug Discovery Laboratory, University of South Alabama, USA.
akeeton@health.southalabama.edu
Gary
Piazza
USA Mitchell Cancer Institute Drug Discovery Laboratory, University of South Alabama, USA.
gpiazza@health.southalabama.edu
hamdy
abdelrahman
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Nahda University, Beni-suef, Egypt
Medicinal Chemistry Department, Faculty of Pharmacy, Assiut University, 71526 Assiut, Egypt
hamdy.abdelrahman@nub.edu.eg
10.21608/ejchem.2020.28992.2624
A series of thirty compounds of quinazolinone-Schiff's base hybrids were rationally designed, synthesized, and evaluated for their in vitro Phosphodiesterase 4B inhibition, anti-lung and anti-colon cancer activities. Compounds 9, 16, 23, 29, 30, 31, 32 and 33, each possessing a tri-hydroxy moiety, showed the highest inhibitory activity (56.05-89.07%) at 10 µM concentration if compared to rolipram. Compounds 16 and 23 showed good anti-lung cancer activity with IC50 1.55 and 1.30 µM, respectively. Moreover, compound 16 showed high anti-colon cancer activity with IC50 0.6 µM. Compound 33 showed good affinity and molecular binding modes towards the key amino acid Gln 443 and Phe 446 for inhibition of the target enzyme. Finally, active compounds showed good ADME calculations.
Quinazolinone,Schiff's,Phosphodiesterase 4B,COPD,lung,Colon,Cancer
https://ejchem.journals.ekb.eg/article_94135.html
https://ejchem.journals.ekb.eg/article_94135_95ec78499ebbbbc60ccbab34380685eb.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Isolation, Characterization of Phytochemical Compounds and Hepatoprotective Activity Evaluation in Rats of Various Extracts from Cyperus esculentus L. tubers
4867
4873
EN
Dina
M
Eskander
Chemistry of Natural Compounds Department, National Research Centre, Dokki, 12622 Cairo, EGYPT
dina226@hotmail.com
mahmoud
I
nassar
0000-0002-2493-4663
Chemistry of Natural Compounds Department, National Research Centre, Dokki, 12622 Cairo, Egypt
mnassar_eg@yahoo.com
Rehab
A
Mohamed
Medical biochemistry Department, National Research Centre, Dokki, 12622 Cairo, Egypt.
roroanas30@yahoo.com
abdel-razik
H
farrag
0000-0002-6121-450X
Department of Pathology, National Research Centre, 33 El Bohouth st., Dokki12622, Cairo, Egypt
abdelrazik2000@yahoo.com
10.21608/ejchem.2020.28752.2627
This study aimed to investigate different phytochemical compounds of Cyperus esculentus tubers grown in Egypt, as affected by different extracts (oil, methanol, chloroform), and evaluate the hepatoprotective activity of these various extracts in rats. Methanol fraction was subjected to silica gel column chromatography, resulted in isolation of three compounds reported for the first time from this plant, oleanolic acid, α –Amyrin 3-0- glucopyranoside, β -Amyrin3-0- glucopyranoside. Their structures were elucidated by spectroscopic methods and comparing data with those reported in literature. GC/MS of oil showed twelve compounds, 9-octadecenoic acid (Z)-,2-hydroxy-1- (hydroxymethyl) ethyl ester represented the major compound, while hexylene glycol was the minor. GC/MS of chloroform gave ten compounds, 9 octadecenoic acid, (E) was the highest peak, and stigmasterol was the lower one. Chloroform, methanol and oil extracts of plant were evaluated for their hepatoprotective activity, in D-galactosamine induced hepatotoxicity in albino rats. The high (500 mg/kg), and low (250 mg/kg) doses of extracts, reduced levels of liver enzymes and total protein towards the normal value, which were comparable to that of reference drug silymarin and D-galactosamine indicating its hepatoprotective activity. Bioactive constituents and hepatoprotective activity of different extracts give this plant its therapeutic effects in addition to nutritional ones.
Cyperus esculentus,Various extracts,Silica gel column chromatography,Terpenes,GC-MS analysis,|Hepatoprotective activity
https://ejchem.journals.ekb.eg/article_94133.html
https://ejchem.journals.ekb.eg/article_94133_cbe571e90c7a0ea7f8bbae7778718bb7.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
An Experimental Study of Mass Transfer coefficient of CO2 absorption using Different Amines in a Packed Column
4875
4881
EN
Zahraa
N.
Abd
https://orcid.org/00
Department of Chemical Engineering, College of Engineering, University of Al-Qadisiyah , AL-Qadisiyah, Iraq
zahraanadhum95@gmail.com
salih
A.
Rushdi
0000-0002-4474-7718
Department of Chemical Engineering, College of Engineering, University of Al-Qadisiyah , AL-Qadisiyah, Iraq
salih.rushdi@qu.edu.iq
10.21608/ejchem.2020.29899.2641
In this work, an absorption technology was used actually to investigation the mass transfer coefficient of carbon dioxide from a gaseous mixture (air, carbon dioxide) in blended solution Monoethanolamine (MEA) and Diethanolamine (DEA) and Triethanolamine (TEA) in a packed column reactor (PCR) . The packed column was made of Plexiglas with 75 cm high and 10 cm inside diameter .The overall mass transfer coefficient (KGa) was evaluated at different operating conditions , gas flow rate, air Flow rate ,liquid flow rate .Where the gas flow rates were 5, 10 and 15 L /min , air flow rate 80,90 and 100 L/h , liquid flow rate 400 ,450,500 mL /min . This experiment by using semi-continuous process with helping centrifugal pump . High-performance gas chromatographic (GC) was performed to evaluate CO2 loading during absorption experiment . The experimental results showed that loading CO2 in the range of 0.461–9.541 (mole CO2 /mole amine), and the maximum value of overall mass transfer coefficient (KGa) was 0.0354 S^-1
CO2 Absorption,Monoethanolamine (MEA),Diethanolamine (DEA),Ttriethanolamine (TEA),overall mass transfer coefficient (KGa),Packed column reactor (PCR),Taguchi Method
https://ejchem.journals.ekb.eg/article_103025.html
https://ejchem.journals.ekb.eg/article_103025_e46d1f1cc7fc7552d81fa9e4ae20f67d.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
QTAIM View of Os–Os Bonding in Triosmium Cluster [Os3(CO)9(µ-ɳ2-C7H3(2-CH3)NS)(µ-CH2)CH3]
4883
4888
EN
Muhsen
Abood Muhsen
Al-ibadi
0000-0001-8639-4888
Department of Chemistry, college of science, University of Kufa, Iraq
muhsen.alibadi@uokufa.edu.iq
Nadia
Ezzat
Al-kirbasee
0000-0003-4808-7830
Department of Chemistry, College of Education for Women, University of Kufa, Iraq
nadiyai.alkurbasy@uokufa.edu.iq
Shatha
Raheem Helal
Alhimidi
Department of Basic Medical Science, College of Dentistry, Al-Muthanna University, Iraq
shatharaheem16@gmail.com
Baker
A
Joda
Department of Chemistry, College of Science, University of Kerbala, Iraq
phdchemistry2008@googlemail.com
manal
Abed
Mohammed
0000-0002-5428-5908
Department of Basic Science, College of Dentistry, University of Kerbala, Iraq
manalabd22@gmail.com
10.21608/ejchem.2020.26737.2546
The topological features of the triosmium cluster [Os3(CO)9(µ-ɳ2-C7H3(2-CH3)NS)(µ-CH2)CH3], containing carbonyl and 2-methylbenzothiazol ide ligands, has been examined using density functional theory (DFT) and QTAIM-based "Quantum Theory Atoms in Molecules". The topological parameters of the electron density in the cluster have been calculated. The QTAIM analysis of the topological features demonstrated that the core part Os3C1 in the cluster is significantly absence a bond critical point and its bond path between Os1-Os3. Whereas, the analysis Os1-Os2 and Os2-Os3 interactions revealed the occurrence of bond paths and bond critical points between these atoms. A multicenter 4c–5e interaction for the Os3C1 core has been proposed. The topological parameters calculation show that the interactions in the bridging 2-methylbenzothiazolide Ligand are a typical for shared shell with the existence of some double-bond character.
DFT calculations,QTAIM,Metal–metal bonds,Organometallic complexes,Topological analysis
https://ejchem.journals.ekb.eg/article_103234.html
https://ejchem.journals.ekb.eg/article_103234_78ad9abe38794e651dea05126218cd40.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
GC/MS Analysis of Lipid Constituents and Antimicrobial Activity of Arum cyrinaicum Extracts
4889
4910
EN
Aziza H.
Zargoun
Alzaeem Alazhary University, Faculty of Education, Chem. Dept., Khartom, Sudan.
Abdelhafeez M. A.
Mohammed
Alzaeem Alazhary University, Faculty of Education, Chem. Dept., Khartom, Sudan.
Khaled A.
Abdelshafeek
0000000194851348
Department of Chemistry, Faculty of Sciences and Arts in Al Mukhwah, Albaha University,
Saudi Arabia.
khabdelhady@gmail.com
Abdalla A
Ibansharrada
Sirte University, Faculty of Medicine, Medical Microbiology dept., Sirte, Libya.
Abdulaziz Ali
Alomari
Department of Chemistry, Faculty of Sciences and Arts in Al Mukhwah, Albaha University,
Saudi Arabia.
10.21608/ejchem.2020.30199.2647
Arum cyrenaicum belonging to family Araceae, it is a perennial herb native to Europe, northern Africa, and western Asia, with the highest species diversity in the Mediterranean region. The main objective of the paper is to isolate, identify lipid constituents and also to evaluation of the potency of different extracts of Arum cyrinaicum (AC) as antimicrobial agents. Different parts of the plant (roots and seeds) were extracted with n-hexane in a Soxhlet for 24 hours till exhaustion. The extracts were fractionated to acetone insoluble fraction, unsaponifiable fration and fatty acids fraction which were identified using GC/MS. <br /> The results of GC/MS analyses of seeds acetone insoluble fraction gave nonacosane (43.3%) and nonacosanol (37.74%) as predominants, while of roots showed the presence of nonacosane (36.1%) as the major hydrocarbons. The unsaponifiable matters of seeds revealed the presence of hexadecane (n-C16, 44.11%) and 9,12-octadecadiene (40.04%). While of roots revealed the presence of a mixture of hydrocarbons and sterols. The GC/MS analysis of fatty acid methyl esters of seeds revealed the presence of myrestic acid (62.9 %) as the main component, while of roots showed the margaric acid (29.2%) and myrestic acid (23.1%) as major acids respectively. The results of antimicrobial activity of different extracts ( using disk diffusion method with determination of inhibitory zone (I.Z.)) against of some microorganisms including G +ve, G – Ve bacteria and fungi proved that, the chloroform and petroleum ether extracts of stem, seeds and roots in addition to the butanol fraction of roots showed high effect against Gram -ve bacteria ( St. aureus).
Keywords: Arum cyrenaicum,Lipid fraction,fatty acids,GC/MS,antimicrobial activity
https://ejchem.journals.ekb.eg/article_97550.html
https://ejchem.journals.ekb.eg/article_97550_55fcbbf820971fb1e6a787ddf6e1a14f.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Preparation And Characterization Of Calixarene Derivative Complexes And Their Application As Catalysis For Ring Opening Polymerization Of e-Caprolactone
4911
4916
EN
Abdulelah
Ismail
Department of Chemistry , College of Science, University of Babylon,Iraq.
abdulelahalbayati022@gmail.com
Yahya
al-Khafaji
0000-0002-4067-9375
Department of Chemistry , College of Science, University of Babylon,Iraq.
yfalkhafaji@gmail.com
10.21608/ejchem.2020.30944.2660
Tripropoxy-p-tert-butylcalix[4]arene and tripentoxy-p-tert-butylcalix[4]arene and their complexes with chromium, cobalt and niobium were synthesized. New compounds were characterized by infrared and nuclear megnatic resonance. All complexes were monometallic system. The ability of the complexes toward polymerization of -caprolactone was investigated by ring opening polymerization mode. One can conclude that the complexes showed modrate activity in term of average molecular weight (Mn) with narrow polydispersity(PDI) and good yield percentage
tripentoxy-p-tert-butylcalix[4]arene,Niobium,Cobalt,Chromium,e-caprolactone
https://ejchem.journals.ekb.eg/article_100937.html
https://ejchem.journals.ekb.eg/article_100937_ee7ffd3e91af7b61ad513cd4e346939e.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Enhancement Adsorption of Lead and Cadmium Ions From Waste Solutions Using Chemically Modified Palmfibers
4917
4927
EN
Walaa
Thabet
Marine Environmental Division, National Institute of Oceanography and Fisheries, Egypt
thabetniof@yahoo.com
Somia
B.
Ahmed
Basic science department, preparatory year deanship, Imam Abdulrahman Bin Faisal, saudi Arabia
sbahmed@iau.edu.sa
ola
Abdelwahab
marine environmental division, National institute of oceanography and fisheries
olaabdelwahab53@gmail.com
Naglaa
F.
Soliman
Technology Management Department, Egypt-Japan University of Science and Technology (EJUST), Alexandria, Egypt
naglaa.farag@ejust.edu.eg
10.21608/ejchem.2020.31220.2663
Efficiently chemically modified adsorbents based upon palm fibers were prepared through chemical treatments of palm fibers by sulfuric acid (PF-AC), oxalic acid as a chelating agent (PF-Chel), HNO3 as an oxidizing agent (PF-OX) and Na2SO3 as a reducing agent (PF-Rd). The four produced adsorbents were applied for the removal of Pb(II) and Cd(II) from synthetic waste solutions. The removal capacity of all chemically modified adsorbents has been investigated through the batch tests to determine the optimum parameters for maximum removal. The kinetics and isotherm studies have been applied to identify the adsorption type. All data in this work has been used as determining factors to predict the adsorption process mechanism. The characterization of the surface of the chemically modified adsorbent [FTIR and SEM] was also studied as another contribution to proving the suggested adsorption mechanism. Experimental data were best fitted by Langmuir model while kinetic results were appropriately expressed by the pseudo-second-order model. The results demonstrated the highest capacity values of 56 and 33 mg/g using PF-Rd for both Pb (II) and Cd (II) ions, respectively. Throughout this study, PF-Rd and PF-OX achieved the maximum capacity with the adsorption of both heavy metals.
Palm fibers,chemical treatment,Adsorption,lead and cadmium ions,Mechanism
https://ejchem.journals.ekb.eg/article_102826.html
https://ejchem.journals.ekb.eg/article_102826_e2142161f62ffa0ceaae949012f8e260.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
High Voltage Cross-Linked Polyethylene Insulator Characteristics Improvement Using Functionalized ZnO Nanoparticles
4929
4939
EN
Elsayied
eldesoky
Polymer and Pigment Department, National Research Centre, 33 El-Bohouth St. Dokki, Giza, 12622, Egypt
alaa_chemist@yahoo.com
Abdelrahman
said
Electrical Engineering Department, Faculty of Engineering at shoubra, Benha University
abdo_eng1987@yahoo.com
Amira
Nawar
0000-0002-4804-9132
Higher Institute for Engineering and Modern Technology, Marg, Cairo, Egypt
eng_amira.2009@yahoo.com
Mousa
Abdallah
Electrical Engineering Department, Faculty of Engineering at shoubra, Benha University
mousa_abdulah@yahoo.com
Samir
Kamel
Cellulose and Paper Department, National Research Centre, 33 El-Bohouth St. Dokki, Giza, 12622,
Egypt
samirki@yafoo.com
10.21608/ejchem.2020.31244.2664
This study aims to develop large-scale commercial Cross-Linked Polyethylene (XLPE) nanocomposites used for industrial applications with power cables insulations. To achieve this goal, XLPE/zinc oxide nanocomposites were prepared with four unique loadings of Zinc Oxid (ZnO) nanoparticles: 0.5, 2, 3.5 and 5 wt.%, in the presence of appropriate coupling agent which used to reduce the agglomeration of nanoparticles and to improve the compatibility inside the polymer matrix. Amino silane was the coupling agent used in this study and the nanocomposites preparation was done using the melt blending method. The morphology and the distribution of nanoparticles inside XLPE polymer were studied using Field Emission Scanning Electron Microscopy (FE-SEM). The mechanical properties were also evaluated. Using Differential Scanning Calorimetry (DSC) and Thermo Gravimetric Analysis (TGA), the thermal properties for nanocomposites were investigated. The dielectric properties of these prepared XLPE/ZnO nanocomposites were studied by measuring the loss tangent (tan δ) and the dielectric constant (ɛr) under frequencies ranging from 1 Hz to 1 MHz. The AC Breakdown Voltage (AC-BDV) was also measured using a controlled high voltage testing transformer (50 Hz) under the sphere-to-sphere field then; the AC dielectric strength was calculated using the Finite Element Method (FEM) technique.
XLPE,Nanocomposites,Zinc Oxide Nanoparticles,electrical,THERMAL,and Mechanical properties
https://ejchem.journals.ekb.eg/article_100938.html
https://ejchem.journals.ekb.eg/article_100938_fc2129b96165a46826efff039a644f81.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Phytochemical Profile and Cytotoxic Activity of Selected Organs of Sambucus nigra L. via Enzyme Assay and Molecular Docking Study
4941
4949
EN
Seham
Salah Eldin
El Hawary
0000-0002-6823
Pharmacognosy Department, Faculty of Pharmacy, Cairo University
seham.elhawary@yahoo.com
Fify
Ibrahim
Fathy
Pharmacognosy Department
Faculty of pharmacy - Cairo University
fifathy@hotmail.com
mona
eltantawy
Department of Medicinal Plants and Natural Products, National Organization for Drug Control and Research, Giza, Egypt
kader48@hotmail.com
Ahmed
El Kerdawy
0000-0003-4127-9055
Pharmaceutical and medicinal chemistry department, Faculty of Pharmacy Cairo University
ahmed.elkerdawy@cu.edu.eg
Mai
Khaled
Mansour
https://orcid.org/00
Department of Medicinal Plants and Natural Products, National Organization for Drug Control and Research, Giza, Egypt
mkm107@live.com
Khaled
Meselhy
Ibrahim
Pharmacognosy Department, Faculty of Pharmacy, Cairo University
kmeselhy@hotmail.com
10.21608/ejchem.2020.31739.2674
The purpose of this study is to shed light on the phenolics content and the presence of different classes of constituents in the flowers, leaves, and stems of Sambucus nigra L. cultivated in Egypt along with screening out their cytotoxic activity. Colorimetric investigation revealed that all tested samples were rich in phenolics. HPLC qualitative analysis revealed the presence of different phenolics including chlorogenic acid and rutin that were isolated and identified using 1H and 13C NMR. The ethanolic extracts of the three organs, together with the two isolated phenolics, were tested for their cytotoxic activity against hepatocellular carcinoma, human lung adenocarcinoma, and human colon carcinoma. All tested samples were able to reduce the viability of the tested cell lines in a dose-response manner comparable to staurosporine as a reference drug. Molecular docking studies were performed for chlorogenic acid and rutin. Their ability to interact with the key amino acids in B-cell lymphoma 2 (Bcl-2) protein binding site rationalizes their pronouncing activity as proven by its docking pattern and docking score. The cytotoxic activity of the flowers, leaves, and stems of Sambucus nigra L. has been attributed to the synergetic effects of phenolic compounds, which affords the basis for investigations as promising candidates for discovering new anticancer drugs.
Sambucus nigra,Phenolics,chlorogenic acid,Rutin,cytotoxic,MTT,Molecular docking
https://ejchem.journals.ekb.eg/article_95791.html
https://ejchem.journals.ekb.eg/article_95791_59a2f9b740f635a55865ac57b0a8aa23.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Nano-synthesis, spectroscopic characterisation and antibacterial activity of some metal complexes derived from Theophylline
4951
4962
EN
Ahmad
H.
Ismail
Mustansiriyah University, College of Science, Department of Chemistry. Iraq.
ah2042013@yahoo.com
Hassanain
K.
Al-Bairmani
Mustansiriyah University, College of Science, Department of Chemistry. Iraq.
dr.hassanain@uomustansiriyah.edu.iq
zainab
sabri
abbas
Mustansiriyah University, College of Science, Department of Chemistry. Iraq.
zainab.alattaby@yahoo.com
ahmed
mahdi
rheima
Wasit University, College of Science, Department of Chemistry. Iraq.
ahmed.rheima@yahoo.com
10.21608/ejchem.2020.32582.2690
The novel was assembled by the ultrasonic sonication method of three new ligand-metal nano complexes with Ni(II), Cu(II), and Co(II) of theophylline derivative. This method was used to produce smaller, small distributed nanoparticles and without any aggregations. Molar conductance, FT-IR,1HNMR, UV–Vis., solubility, flame atomic absorption, and (C.H.N) elemental analysis were used to describe and to suggest the structure of the new ligand and nanocomplexes. Engagement of all spectroscopic data indicates that the new ligand (L) acts as a bidentate ligand with its metal ions. The molar conductance reveals that the nanocomplexes were non-electrolytes. The size and morphology of nano complexes measured by TEM were in range (12-18) nm. <br /> The biological activities of the synthesised metal nano complexes were assayed against four types of bacterial strains, Staphylococcus aureus, Bacillus subtilis (gram-positive bacteria) and Klebsiella pneumonia, Escherichia Coli (gram-negative bacteria). The results show remarkable leverage compared to the parent ligand in the present nano complexes.
Nanocomplexes,new ligand,theophylline derivative,Ultrasonic Sonication,bacterial strains,TEM
https://ejchem.journals.ekb.eg/article_102749.html
https://ejchem.journals.ekb.eg/article_102749_afbff7c95da643cf76c61a29d3c6cfe0.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Studying the Treatability of Different Types of Nanoparticles for Oil Content Removal from Oily Wastewater Produced from Refinery Process
4963
4973
EN
Saja
Mohsen
Alardhi
Nanotechnology Advanced Material Research Center, University of Technology, Iraq
sajamohsen1987@yahoo.com
Forat
Yasir
AlJaberi
Chemical Engineering Department, College of Engineering, Al-Muthanna University, Al-Muthanna, Iraq
furat_yasir@yahoo.com
Laith Majeed
AlSaedi
Missan Oil Company
10.21608/ejchem.2020.11981.1752
Huge amount of oily wastewater is annually discharged from several activities such as oil refineries, chemical and petrochemical industries. Several methods are employed for the treatment of oily wastewater including physical, chemical, and biological techniques in order to minimize the harmful impacts before being reused. The present study compares the treatability among three different types of nanoparticles NPs (MCM-41, MWCNT and BaFe2O4) to remove oil content from real oily wastewater discharged from refinery process under the effect of the operational variables which are the dose of the effective NPs (0.025-0.10 g), agitation speed (100-250 rpm), and the contact time (5-120 min) using batch-scale. RSM design method and Minitab program were performed to design the experiments and to estimate the mathematical correlations and the optimum values of the operational variables. Various devices were employed to test the properties of nanoparticles such as X-ray diffraction, SEM and FTIR. The results revealed that the (MCM-41) type possesses the higher treatability in comparison to other types. Moreover, the Langmuir isotherm gives a better fit than the Freundlich isotherm model. The optimum values of the operational parameters obtained were 0.063g, 162rpm and 120min for the dosage of MCM-41 NPs, agitation speed and the contact time respectively. The oil content removal efficiency at these conditions of the optimum values was 98.3% as observed which proofs the treatability of MCM-41 NPs in case of real oily wastewater.
Refinery wastewater,Oil content,Wastewater treatment,Nanoparticles,RSM design,Adsorption,Adsorption isotherm models
https://ejchem.journals.ekb.eg/article_103744.html
https://ejchem.journals.ekb.eg/article_103744_c064be40a522b38f1124139ce8ece565.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
A Study of the Component Formats Effect on I,onization Constants for A Number Schiff Pyridine Water and Ethanol with Variant Temperature Degrees
4975
4985
EN
Fedaa
Merie
Lecturer, Department of Chemistry, College of Education for Pure Sciences, University
of Mosul, Iraq
meriefedaa65@gmail.com
10.21608/ejchem.2020.21228.2266
This investigation was started by synthesis of four pyridine Schiff bases from the mother compound (Salicyladehyed), whose nomenclatures and structures are seen in the text. The structures of these imines were well confirmed from U.V. and I.R. spectra at melting points. The main objective of this study is the determination of Ka values for these mentioned imines at temperature rang (20-60) Co by conductivity measurement method. This method as found, Simple, precise and accurate. The thermodynamic parameters of ionization for acids were also estimated. This shows that the process of ionization of acidic compounds under study in water Solvent is non spontaneous ( +∆H) and is accompanied by an increase of order ( -∆S). A direct linear plots were obtained between pka for any acid versus the dielectric constant of acid and versus the dietetic constant of ethanol at the five different temperatures. <br /> Finally, a suitable interpretation for any one of these thermodynamic parameters are given and discussed
Conductivity,pka,Phenolic Schiff,Thermodynamic of Ionization
https://ejchem.journals.ekb.eg/article_94127.html
https://ejchem.journals.ekb.eg/article_94127_f8dbe1c0ab0734c85bc88f56ed2da18d.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Application of Jute Polyethylene Composites for Storage Tank as a Function of Fiber Treatment
4987
4995
EN
Md. Faruk
Hossen
Department of Chemistry, Faculty of Science, University of Rajshahi, Rajshahi-6205, Bangladesh.
fhossen.chem@ru.ac.bd
Md. Ali
Asraf
Department of Chemistry, Faculty of Science, Rajshahi University, Rajshahi-6205, Bangladesh
asraf.chem@ru.ac.bd
Md. Kudrat
Zahan
0000-0001-8159-5293
Department of Chemistry, Faculty of Science, Rajshahi University, Rajshahi-6205, Bangladesh
kudrat.chem@ru.ac.bd
C. M.
Zakaria
Department of Chemistry, Faculty of Science, Rajshahi University, Rajshahi-6205, Bangladesh
choudhuryzakaria@yahoo.com
10.21608/ejchem.2020.28220.2595
The jute polyethylene nanocomposites were manufactured using the hot-press technique with different fiber weight fractions. The hydrophilic nature of fiber exhibited poor interfacial interaction to hydrophobic polymer matrix. Three types of chemical reagents such as: benzenediazonium salt (BDS), propionic anhydride (PA), and 3-isocyanatopropyl triethoxysilane (Silane) have been used to reduce hydrophilicity of jute fibers. The chemical resistance tests of prepared composites were performed in order to observe whether these composites are resistant to various chemicals such as: acids, alkalis, and solvents. It was observed that the fabricated composites were resistant to all chemicals except carbon tetrachloride. The treated jute composites showed higher chemical resistance than raw jute composite and silane treated jute composite gave the highest resistance which can be suggested for making the water and chemical storage tanks.
Jute fiber,chemical treatment,composites,chemical resistance,Storage tank
https://ejchem.journals.ekb.eg/article_99691.html
https://ejchem.journals.ekb.eg/article_99691_22f6876e2db00e0a1a0c735b181eba85.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Synthesis of Novel Coumarin Derivatives Bearing Phosphor Ester Motifs and Evaluation of their Antioxidant Activities
4997
5009
EN
Maha
Khidre
Pesticide Chemistry Department,
National Research Centre (NRC), Giza, Egypt
mdkhedr@yahoo.com
Eman
Sabry
Pesticide Chemistry Department,
National Research Centre (NRC), Giza, Egypt
emy_esa@yahoo.com
Abdel-Tawab
H
Mossa
0000-0002-8112-8553
Environmental Toxicology Research Unit (ETRU), Pesticide Chemistry Department,
National Research Centre (NRC)
, Giza, Egypt
abdeltawab.mossa@yahoo.com
Abeer
Shaddy
0000-0003-4463-5617
Pesticide chemistry, National Research Centre, Egypt
abraouf1234@yahoo.com
10.21608/ejchem.2020.31702.2676
phosphoramidate, phosphoranylidenetriazene, and azaphosphole derivatives can be respectively formed when the substituted azidocoumarin 1 reacted with trialkylphosphites (TAP), dialkylphosphonates (DAP), and tris(dialkylamino)phosphines. The known triazinedione was revealed to be a side product in the reactions of carbaldehyde 1 with TAP and tris(dialkylamino)-phosphines. In the same context, when the starting coumarin 16 was allowed to react with P (III) reagents, chromen phosphoramidates and chromen phosphoric triamide derivatives were obtained via Staudinger reaction. Contrary to that pathway, phosphoranylidenetriazen chromen derivative could be isolated and identified when coumarin 16 was allowed to react with tris(diethylamino)-phosphine. The antioxidant activities of 6-newly products were evaluated. The results showed that two from the six screened compounds exhibited good antioxidant activities.
Azidocoumarin,phosphoramidates,Azaphospholes,Chromen phosphoric triamide,Antioxidant activity
https://ejchem.journals.ekb.eg/article_101435.html
https://ejchem.journals.ekb.eg/article_101435_b80e9442bb290616dda4a71e636a9950.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Synthesis of Super Magnetite(Fe3O4)/ Bentonite Nanocomposite for Efficient Remediation for Industrial Wastewater Effluents
5011
5026
EN
Asmaa
Elsayed
0000-0003-1228-5974
Egyptian Petroleum Research Institute (EPRI), Nasr City, Cairo, Egypt
asmaa.elsayed70@yahoo.com
Doaa
Osman
Egyptian Petroleum Research Institute (EPRI), Nasr City, Cairo, Egypt
di_osman@yahoo.com
Sayed
Attia
Egyptian Petroleum Research Institute (EPRI), Nasr City, Cairo, Egypt
sayedkhairy98@yahoo.com
Hayam
Ahmed
Faculty of Science, Al-Azhar University
ha_ahmed@azhar.edu.eg
Eman
Shoukry
Faculty of Science, Al-Azhar University
eman_shoukry2002@yahoo.com
Ghada
A.
Mahmoud
0000-0001-8335-7766
National Center for Radiation Research and Technology, Atomic Energy Authority, Cairo, Egypt.
ghadancrrt@yahoo.com
Yasser
Moustafa
Egyptian Petroleum Research Institute (EPRI), Nasr City, Cairo, Egypt
ymoustafa12@yahoo.com
Afaf
Taman
Egyptian Petroleum Research Institute (EPRI), Nasr City, Cairo, Egypt
afaf.taman@gmail.com
10.21608/ejchem.2020.27520.2574
The goal of the current work was to prepare magnetite/bentonite nanocomposite and testing for expulsion effectiveness of cationic methylene blue (MB) and anionic methyl orange (MO) dyes, phenol and Ni2+ from industrial wastewater in individual and combined systems. Batch experiments have been done to observe the best adsorption by altering various parameters such as temperature, pH, the dose of adsorbent, initial pollutants concentration and contact time. The results demonstrated that the optimum pH for removing (MB) was 9.0, (MO) was 4.0, phenol was 7.0 and 4.0 for Ni2+. The optimum concentration, temperature, contact time and adsorbent dose were 100 mg/L, 80 oC, 120 min and 1g of adsorbent, respectively. The sorption process was modeled utilizing Langmuir and Freundlich equations. The adsorption isotherm demonstrated a superior fit to Freundlich than Langmuir equation. The analysis was also modeled using the pseudo-first and second order equations. The pseudo-second-order equation gave better fit with an R2 value; 0.999 for all pollutants. This implies that our proposed magnetite\bentonite nanocomposite can be utilized as a cheap and excellent adsorbent for expulsion of cationic and anionic dyes, phenol and cationic heavy metal ions from industrial wastewater.
Adsorption,dye removal,heavy metal ions,Nanocomposite,Wastewater treatment
https://ejchem.journals.ekb.eg/article_94131.html
https://ejchem.journals.ekb.eg/article_94131_0cd8a8b246b518679e0c2a28848d86a1.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Modafinil Alleviates Rotenone-Induced Neurochemical changes and Striatal Neurodegeneration via Inhibiting Oxidative Stress and Neuroinflammation
5027
5037
EN
Sara
Ahmed
Seadawy
Biochemistry department,
Genetic engineering and biochemistry research division,
National Research Centre.
El-Behowth St.,
Dokki, Cairo, Egypt.
saraseadawy86@gmail.com
Marwa
El-Sayed
El-Shamarka
0000-0002-9752-6556
Medical Research Division Research division,Narcotics, Ergogenics and Poisons Department,Cairo,Egypt
marwaelshamarka@gmail.com
Mie
Afify
0000-0002-3187-1322
Biochemistry Dept. NRC
mieafify@yahoo.com
Omar
Abdel-Salam
0000-0002-4450-1582
Department of Toxicology and Narcotics, National Research Centre, Dokki, Cairo, egypt
omasalam@hotmail.com
Dalia
abouefadle
Department of Pathology, Medical Division, National Research Centre, Cairo, Egypt
abouelfadl808@gmail.com
10.21608/ejchem.2020.47734.2975
Objectives of study are around investigation the effect of the central nervous system stimulant modafinil on brain striatum neurodegeneration caused by subcutaneous (s.c.) rotenone administration in rats, further, the possible modulation by modafinil on L-dopa effect on oxidative stress, inflammation and nigrostriatal cell damage. Seven groups of Male albino mice received dimethyl sulfoxides.c., rotenone (1.5 mg/kg, s.c., 3 times per week), rotenone/L-dopa (25 mg/kg, p.o., daily), rotenone/modafinil (0.1, 0.2 and 0.3 mg/kg respectively, p.o., daily), rotenone/L-dopa/modafinil (0.2 mg/kg, p.o. daily). The treatment was continued for 2 weeks. Mice were tested for behavioral changes 24h after the end of treatments.Mice were evaluated for brain biochemical markers of oxidative stress (lipid peroxidation, reduced glutathione, and nitric oxide), pro-inflammatory factors (tumor necrosis factor-α, interlukin-1beta) and dopamine level. Histopathologic examination and the expression of the anti-apoptotic protein caspase-3 were also performed. Rotenone significantly elevated oxidative stress and pro-inflammation, decreased dopamine, induced substantianigra damage with caspase-3-mediated apoptosis respectly to the control levels. Results of modafinil or its combination with L-dopa may have potential therapeutic effect in Parkinson’s disease by decreasing pro-inflammation and oxidative stress, increasing dopamine, preventing the development of neuronal damage and reducing caspase-3 expression in the striatum.
Modafinil,Brain oxidative stress,Neuro-inflammation,apoptosis,nigrostriatal damage,Rotenone,L-dopa
https://ejchem.journals.ekb.eg/article_125316.html
https://ejchem.journals.ekb.eg/article_125316_ede8f74d4eeea69b76520837bb8b2451.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Diterpenoids Profile of E. paralias and E. geniculata Using UPLC-ESI/MS Spectrometry
5039
5053
EN
Afaf
Said
Ghani
department of Pharmacognosy, Pharmacy , Zagazig University.
hamedzhaghloul.cfc@gmail.com
sayed
abdelhamid
eltomy
https://orcid.org/00
National Research centre
Tanning lab.
sayedeltomy@yahoo.com
Wagdi
Ibrahim
eldougdoug
Department of Organic Chemistry, Faculty of Science, Banha University
eldougdoug@yahoo.com
hanaa
mohamed
hassan
pharmacognosy department, zagazig university.
hanaazain111@yahoo.com
Wafaa
Hassan
Badr
Department of Pharmacognosy Faculty of Pharmacy, Zagazig University
wafbadr@yahoo.com
10.21608/ejchem.2020.25113.2486
Euphorbia species contain series of macrocyclic diterpenoids which present as mono, di and sometimes triesters and were reported to possess several and diverse biological activities. The aim herein was to use the positive ion mode ultraperformance electron spray ionization mass spectroscopy (UPLC-ESI-MS) as an analytical tool for rapid screening and tentative identification of diterpenoids in the methylene chloride fractions of Euphorbia paralias and Euphorbia geniculate. The identification of compounds was based on ESI-MS and ESI-MS/MS fragmentation pattern, in addition to comparison with reported literature. Five classes were determined including tigliane, ingenane, lathyrane, daphnane and jatrophane diterpenoids esters. Each class of the detected diterpenoids obtained its characteristic ESI-MS/MS fragmentation which facilitates its identification. As a result, a total of fifty two diterpenoids were identified and characterized in E. paralias and E. geniculate. All of these compounds are first report in the two plants by this method. The results demonstrated that the used method could be a rapid, effective analytical tool for screening and characterization of diterpenoids in the complex systems of plants extracts.
Keywords: Euphorbia,terpenoids,UPLC-ESI-MS,ingenanes,and tiglianes
https://ejchem.journals.ekb.eg/article_85811.html
https://ejchem.journals.ekb.eg/article_85811_38504db48f15a3e78e1c03a12abdcf82.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Geochemical and Mineralogical Evaluation of Black Shale and its Hydrocarbon Potentiality,Southwest Sinai, Egypt
5055
5070
EN
Esmat
Abou El-Anwar
0000-0001-5947-2254
Prof. of Geochemistry Geological Sciences Dept., National Research Centre, Dokki, Giza, Egypt.
abouelanwar2004@yahoo.com
Salman
A.
Salman
0000-0002-2173-0438
Geological Sciences Dept., Inorganic Chemical Industries and Mineral Resources Research Division, National Research Centre
sal_man19@yahoo.com
Doaa
Mousa
Exploration Department, Egyptian Petroleum Research Institute
doaa2_ali@hotmail.com
Sami
K
Aita
Nuclear Materials Authority, Egypt
sami_aita@yahoo.com
10.21608/ejchem.2020.44732.2907
The investigation of new energy sources become one of the world tasks in the last decades. Oil shale is one of the promising energy sources and widespread in many parts of Egypt. So, this work was conducted to investigate hydrocarbon potentiality, geochemistry and environmental impact of Magharet El Maiah Formation black shale, Southwest Sinai. This shale is of Carboniferous ageand composed mainly of kaolinite, montmorillonite and illite in a decreasing order with quartz and pyrite as non-clay minerals.They are deposited under oxic non-marine condition. Chemical analysis revealed that paleo-redox elements for the studied area were deposited under oxic environment and subjected to highly intensive chemical weathering.The calculated pollution indices indicated the mostly studied Black shale isn’t polluted. However, the studied black shale is enriched with some economic trace elements than the UCC and PAAS, especially Pb.All the studied samples are of indigenous origin. The organic richness of the studied samples ranges from fair to excellent total organic carbon content. The kerogen type is III; the organic matter reaches the overmature stage and can be generate dry gas.
Sinai,Black Shale,pollution,Kerogen,Palynofacies,Hydrocarbon potentiality
https://ejchem.journals.ekb.eg/article_126524.html
https://ejchem.journals.ekb.eg/article_126524_08d9eba747872306023a3c94e53e55b4.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Bioactivity Guided Investigation of Caryota mitis & Caryota urens Chemopreventive Activity via In Vitro and In Silico Studies
5071
5086
EN
Ahmed
Ragab
Hamed
0000-0003-2691-7725
Department of Phytochemistry, Pharmaceutical and Drug Industries Research Division.
n1ragab2004@yahoo.com
Aisha
H.
Abou Zeid
0000-0001-7807-9722
Pharmacognosy Department, Pharmaceutical and Drug Industry, National Research Center
abouzeida@yahoo.co.uk
Hanaa
El-Rafie
0000-0003-1230-0601
Pharmacognosy department, Pharmaceutical and drug industry, National Research center
hanaelrafie@yahoo.com
Zeinab
A.
Kandil
0000-0002-3339-382X
Pharmacognosy Dept., Faculty of Pharmacy-Cairo University, Cairo, Egypt
zeinababdelazizmohamed@yahoo.com
Radwa
H.
El-Akad
0000-0003-0245-1406
Pharmacognosy department- National Research Center- Cairo, Egypt
radwa.hassan.elakad@gmail.com
Mohamed
Farag
0000-0001-5139-1863
Faculty of pharmacy, Cairo university
mfarag73@yahoo.com
10.21608/ejchem.2020.30737.2655
The study highlights for the first time the potential role of Caryota mitis and Caryota urens (family Arecaceae) in cancer chemoprevention as NQO1 enzyme inducers. Among the tested leaf extracts of different solvent polarities, C. urens petroleum ether leaf extract showed the most potent induction of NQO1 enzyme activity (4.79 times to vehicle control) via DCPIP assay and a significant difference was observed at concentration 25 μg/mL via NQO1 western blot analysis. First comparative GC/MS analysis of both species' petroleum ether leaf extracts was conducted to reveal for 35 vs 34 compounds in C. mitis and C. urens unsaponifiable matter, respectively, and 29 vs 15 fatty acids as methyl esters, respectively. Isolation attempts from the active C. urens extract resulted in the identification of five compounds i.e. oleanolic acid (T1), ursolic acid (T2), α-tocopherol (T3), palmitic and stearic acids (T4 & T5) using different spectroscopic techniques; where T1 and T3 are first time to be identified in C. urens. Assessment of the isolated compounds' chemopreventive activity was conducted via in silico molecular modeling against KEAP-1 –Nrf2 complex involved in of NQO1 where T1, T2 and T3 showed promising docking score of -7.7, -7.9 and -7.05 kcal/mol, respectively, compared to -8.2 kcal/mol for 4'-bromoflavone as a positive control.
Caryota,NQO1 inducers,Nrf2/Keap-1 docking,Chemoprevention,GC/MS,Triterpenes
https://ejchem.journals.ekb.eg/article_97551.html
https://ejchem.journals.ekb.eg/article_97551_0c0901da49fa626f4e8285cff99bafd9.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
09
15
Hepatoprotective activities of thyme (Thymus vulgaris L.) in rats suffering from obesity.
5087
5101
EN
Hassan
Mohamed
Sobhy
Natural Resources Department, Faculty of Africa Postgraduate Studies, Cairo University, Egypt.
hassansobhy20@yahoo.com
Naglaa
Hassanen Mohamed
Hassanen
Special Food and Nutrition Department, Food Technology Research Institute, Agriculture Research Center, Giza, Egypt
naglaahassaneen@yahoo.com
Mamdouh
Ahmed Ibrahim
Ahmed
0000-0003-1592-9843
Special Food and Nutrition Department, Food Technology Research Institute, Agriculture Research Center, Giza, Egypt
mamdoprof@gmail.com
10.21608/ejchem.2020.37364.2792
Thyme (Thymus vulgaris L.) is medicinal plant in the lamiaceae family which is cultivated worldwide for cosmetic, culinary and medical uses. The current study aimed to investigate the impact of thyme on the nutritional parameters of obese rats. Phenolic and flavonoid components were detected in dry thyme powder by HPLC-UV and thyme essential oil was analyzed by GC-MS. In the biological experiment, the study included 30 male rats of weight approximately 200 grams which were divided into 5 groups; each group comprising 6 rats. Group (G1) rats were fed on basal diet, serving as a negative control group (N-control), while group (G2) rats were fed on a high-fat diet (fat percentage 15%) (P-control).The same diet used in (G2) was given to group (G3) but along with orlistat supplementation (2mg/Kg BW rat/day) using a stomach tube. Similarly, the rats of groups (G4 and G5) received HFD and supplemented with thyme powder (3g/100g diet) and thyme essential oil (0.6g/100g fat), respectively. The obtained results indicated that, dry thyme powder composition included high concentration of phenolic compounds such as ellagic acid and salicylic acid, as well as high concentration of flavonoids was hesperidin. The major constituent of thyme essential oil was thymol. After 8 weeks, the rats fed on HFD and supplemented with different treatments (G3, G4, and G5) showed a significant decrement in glucose levels. In addition, the treatments also showed significantly enhanced lipid profiles, liver functions, and total antioxidant capacity. However, the activities of catalase and glutathione reduced were significantly elevated in the blood of thyme powder and essential oil-treated groups. Moreover, malondialdehyde were significantly decreased in the treated groups. The induction of redox enzymes serves as a dependable marker for assessing the antiperoxidative effect of herbs; hence, this study revealed the role of thyme powder and essential oil treatment in the reduction of histopathological and liver abnormalities associated with obesity.
thyme,essential oil,HPLC,GC-MS,Obesity
https://ejchem.journals.ekb.eg/article_112669.html
https://ejchem.journals.ekb.eg/article_112669_69850b576c1ceca38af0adfff55b3906.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Impact of Drip and Gated Pipe Irrigation Systems, Irrigation Intervals on Yield, Productivity of Irrigation Water and Quality of Two Common Bean (Phaseolus vulgaris L) Cultivars in Heavy Clay Soil
5103
5116
EN
E. M.
Okasha
Water Relation and Field Irrigation Dept. National Research Centre
I. M.
El-Metwally
Botany Department, National Research Centre
Noura M.
Taha
Horticulture Department, Faculty of Agriculture, Ain shams University, Egypt,
reda
khaled
darwesh
Crop Water Requirement Dep. Soils, Water and Environment institute (SWERI), Agricultural Research center (ARC), Egypt.
r_darwesh82@yahoo.com
10.21608/ejchem.2020.49013.3001
Two field experiments were conducted during the two successive winter growing seasons of 2018/2019 and 2019/2020 at Kafer El-Khawazim, Talkha district, Dakahlia Governorate, Egypt to study the effect of irrigation systems (drip and gated pipe) and irrigation intervals (5, 7 and 9 days) on some evaluation criteria were studied to determine the best conditions to increase yield, productivity of irrigation water and quality of beans under heavy clay soil conditions. Data indicated that the highest value for water applied recorded under gated pipe irrigation and interval 9 days. For concerning irrigation application efficiency for drip irrigation were occurred with 5 days interval, while the lowest value was recorded under gated pipe system and irrigation interval 9 days. The highest values for vegetative growth, yield components, seed yield, productivity of irrigation water and quality traits of common bean recorded under drip system comparing with gated pipe and for irrigation interval, the highest values recorded with 7days, while they decreased slightly at 5 days and then decreased at 9days. The best value for the vegetative growth, yield components, seed yield, productivity of irrigation water and quality traits of common bean were occurred with recombinant inbred line "RIL 115" compared to common bean (Navv bean). Finally, using drip irrigation system and irrigation interval at 7 days and selection RIL 115 are highly recommended to increase and improve the yield, productivity of irrigation water and quality traits of common bean under clay soils conditions.
common bean,Drip irrigation,gated pipe,Irrigation intervals,water productivity,yield
https://ejchem.journals.ekb.eg/article_125552.html
https://ejchem.journals.ekb.eg/article_125552_1f068d779bb07ee6a42419bfed54823d.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Formulation of Multi-Functional Omega-3 Oil Rich Microcapsules by Spray Drying Methodology
5117
5136
EN
Said
Hamed
0000-0001-5086-7110
Fats and Oils Department, National Research Centre, El-Buhouth St., Dokki,
Cairo, Egypt, Postal code 12622
saidfatouhhamed123@gmail.com
Kawther
Elshafei
0000-0003-1035-9845
Dairy Science Department, National Research Centre, El-Buhouth St., Dokki,
Cairo, Egypt, Postal code 12622
dr.k.elshafei@hotmail.com
Hoda
El-Sayed
0000-0003-1560-5523
Dairy Science Department, National Research Centre, El-Buhouth St., Dokki,
Cairo, Egypt, Postal code 12622
drhodasamir@yahoo.com
Ghada
Abo-Elwafa
0000-0002-2681-6249
Fats and Oils Department, National Research Centre, El-Buhouth St., Dokki,
Cairo, Egypt, Postal code 12622
gada_abo@hotmail.com
Sherine
Afifi
0000-0002-8284-0374
Fats and Oils Department, National Research Centre, El-Buhouth St., Dokki,
Cairo, Egypt, Postal code 12622
shi.moh.afifi@gmail.com
Hamdy
Zahran
0000-0003-2500-8378
Fats and Oils Department, National Research Centre, El-Buhouth St., Dokki,
Cairo, Egypt, Postal code 12622
hazahran23@gmail.com
10.21608/ejchem.2020.43946.2891
This work was proposed to prepare multi-functional omega-3 oil based microcapsules. Rosemary (Rosmarinus officianlis L.) extracts as potential active compounds were used to stabilize these omega-3 rich microcapsules against both oxidation and microbes. Solvents of different polarities as well as ultrasonic-assisted water extraction (UAE) technique were tested for preparing promising extracts. Results demonstrated that water extract showed the highest phenolic extract as well as highest radical scavenging activity (RSA %) even when compared with BHT as a reference synthetic antioxidant. However, the potency of ultrasonic-assisted water extract as a radical scavenger was greatly enhanced specifically at a temperature of 45C and 30 min extraction time. Regarding the antimicrobial activity, although giving highest total phenolics and RSA %, water extract had no antimicrobial activity against both Gram negative or Gram positive bacteria (at concentration range 0.25 –15 %) while methanol extract revealed inhibitory activity against all tested pathogens at concentration of 5 % or higher. Moreover, methanol extract didn’t affect the survivability of the beneficial bacteria of lactobacilli strains. Finally, according to the results the microcapsules prepared by spray drying method exhibited better protection of omega-3 rich oils and also the yogurt fortified with spray-dried fish oil capsules had higher score in sensory evaluation.
Omeg-3 rich oils,rosemary extract- ultrasound assisted extraction - antioxidant activity- antimicrobial activity
https://ejchem.journals.ekb.eg/article_119988.html
https://ejchem.journals.ekb.eg/article_119988_7f9b6b93668e3b9a7eef3937aa01dac1.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Production of Pure Biofuel and Some Chemicals From Waste Soap Stock
5137
5144
EN
Eslam
Al Amrousi
0000-0001-6778-5365
Petroleum Applications Department, Egyptian Petroleum Research Institute, Nasr City, Cairo,
eslamalamrousi@yahoo.com
salwa
Abdallah
El - Khatib
Petroleum Refining Department, Egyptian Petroleum Research Institute, Nasr City, Cairo
selkhatib43@yahoo.com
Fawzi
Al Amrousi
0000-0001-8935-6705
Petroleum Applications Department, Egyptian Petroleum Research Institute, Nasr City, Cairo,
fawzialamrousi@yahoo.com
Eman
Fawzi
Al-Amrousi
0000-0002-5683-9919
Fats and oils Dep., Food and nutrition Division, National Research centre, Doki, Egypt
menoamrousi@yahoo.com
10.21608/ejchem.2020.46537.2950
The non-esculent soap stock oil was employed for producing some rare chemicals, along with certain fractions of biofuels akin to those engendered from petroleum sources. This inexpensive feed stock was hydrotreated using NiMo/Al2O3 in the sulfided form as a catalyst. The applied process was accomplished in a continuous micro-reactor, under high pressure of hydrogen. <br /> The hydroprocessed oil was treated chemically for separating its liquid hydrocarbons from the fatty acid constituents. The fatty acids were esterified to be transformed to the corresponding methyl ester. The products were identified via the gas chromatographic technique. <br /> The results reflect that the acquired hydrocarbons are clean and free from oxygenated compounds, in addition to sulfur, which has an adverse impact on the environment and on the performance of engines, so it can be used as a high – grade biofuel and also as pure chemicals. Furthermore, the prepared fatty acids are characterized by their low molecular weight, with carbon numbers in the range of C5 to C22, including those with odd carbon numbers that regarded as very rare components in nature. Hence this work offers the ability for obtainment precious products from a cheap material.
biofuel,Esterification,fatty acids,hydrotreating process,soap stock,vegetable oils
https://ejchem.journals.ekb.eg/article_121574.html
https://ejchem.journals.ekb.eg/article_121574_702b3560cda08177a0b8406a860d912a.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
The Effect of Fiber-Adhesive Composite on Bond Strength of Plastic Plates- Part I: Adhesion Type & Thickness
5145
5159
EN
Ebrahiem
Ebrahiem
Chem. Eng. Dept., Faculty of Eng., Minia university. Minia, Egypt.
prof.ebrahiem@mu.edu.eg
Ahmed Abdelaziz
Noaman
Chem. Eng. Dept., Faculty of Eng., Minia university. Minia, Egypt.
Ibrahim Hamed M.
Aly
Chem. Eng. Dept., Faculty of Eng., Minia university. Minia, Egypt.
Mostafa A.
Abdel-Rahman
Production & Design Engineering, Faculty of Engineering - Minia University, Egypt
10.21608/ejchem.2020.15361.1932
More than 60 percent of the world’s oil and gas transmission pipelines are more than 40 years old and for the most part in urgent need of rehabilitation in order to re-establish the original operating capacity. So, these steel pipelines may suffer from internal or external metal loss due to erosion and/or corrosion. <br /> Reinforced Epoxy materials as an alternative to carbon steel pipes are highly useful especially for corrosive. They present an exceptional arrangement of chemical resistance, thermal resistance, high mechanical properties which is achieved by the selection of highly performing components and a properly designed structure. The reinforced polymers like poly vinyl chloride (PVC) for natural gas transportation at high pressure (approximately 5 MPa) are investigated to be used instead of steel pipeline. Polyvinyl chloride (PVC) polymer is used. Three types of resins (epoxy, polyester and poly vinyl acetate) were used with different thickness. These resins can make uniform distribution of stress on the reinforced polymer.<br /> The results shows the strength of PVC/PVC sandwich plates is higher than PVC/PVC single plate by 50 % for epoxy, 65% for polyester and 100% in case of poly vinyl acetate, moreover the poly vinyl acetate gave best results for energy to fraction and adhesion shear tests.
Keyword: Oil industry,corrosion and/or erosion,steel pipeline,epoxy resins. PVC
https://ejchem.journals.ekb.eg/article_97555.html
https://ejchem.journals.ekb.eg/article_97555_42254ef72ab4240271b0cbb053809a85.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Desalination Performance of Thin-film Composite Forward Osmosis Membranes Based on Different Carbon Nanomaterials
5161
5173
EN
Amira
Shawky
Sanitary and Environmental Institute (SEI), Housing and Building National Research Center (HBRC), Dokki, Giza, Egypt, 1770
mira_halim483@yahoo.com
Yousra H.
Kotp
Hydrogeochemistry Dept., Desert Research Center, El Mataryia Cairo, Egypt, 11753.
M.A.
Mousa
Chemistry Department, Faculty of Science, Benha University, Benha, Egypt
Mostafa M. S.
Aboelfadl
Hydrogeochemistry Dept., Desert Research Center, El Mataryia Cairo, Egypt, 11753.
E. E.
Hekal
Department of Chemistry, Faculty of Science, Ain Shams University, Abbassia, Cairo, Egypt, 11566.
10.21608/ejchem.2020.27083.2646
The incorporation of nanomaterials in thin film composite (TFC) has provided a new way to increase the permeability of the forward osmosis membrane during the desalination of water. In this research graphene oxide (GO), reduced graphene oxide (rGO) and carbon nanotube (MWCNT) was prepared and introduced into a polyamide layer to form TFC membrane via interfacial polymerization reaction. The properties of the membranes were characterized by using ATR- FTIR, SEM and water contact angle measurements. The obtained results illustrated that a TFC-FO membrane doped with GO (0.7wt%) has a high water flux (27.15 L m-2h-1) while membrane doped with rGO (0.5wt%) exhibits water flux (24.05 L m-2h-1), and the membrane doped with MWCNT (0.5wt%) has water flux (21.67 L m-2h-1) compared with pure membrane with water flux of (10.24 L m-2h-1).
Thin-film nanocomposite Membrane Forward osmosis (TFN),Forward osmosis (FO),graphene oxide (GO),reduced graphene oxide (rGO),multiwall carbon nanotubes(MWCNTs),polysulfone substrate
https://ejchem.journals.ekb.eg/article_97554.html
https://ejchem.journals.ekb.eg/article_97554_05e9f5828d5e19afcac1233ee252eadd.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Polyphenol oxidase activities by cobalt (II) complex with Benzopyran Derivatives, Synthetic, Characterization, Kinetics Study and Molecular Modeling Studies
5175
5181
EN
Mohamed
Mahmoud
ELsayed
Chemistry Department, Faculty of Science &amp; Arts Al-Mukhwah, Al-Baha University, Al-Baha, Saudi Arabia
omarmoaz180@yahoo.com
10.21608/ejchem.2020.15110.1913
The Cobalt complex of 2-Amino-4-(2-chloro-5-nitrophenyl)-5,6,7,8-tetrahydro-7,7-dimethyl-5-oxo- 4H-chromene-3-carbonitrile)( CNB) was synthesized. The organic ligand CNB was previously synthesized using an environment friendly method using microwave irradiation. The cobalt complex cobalt (II)-CNB was characterized by different tools such as IR, electronic spectroscopy, elemental analysis, Thermal analysis and mass spectroscopy. The mode of metal binding shows that the cobalt binds with the ligand through the nitrogen atoms of the amino and cyanide groups. The cobalt complex cobalt (II)-CNB has been used in the homogenous oxidation of polyphenol 1, 2, 3-trihydroxybenzene in presence of a green oxidant H2O2 as biomimetic metalloenzymes. Kinetic parameters were calculate kcat 1.0971×10-5S-1, KM1.412 ×10-2 M, Vmax 7.68×10-4MS−1 and catalytic efficiency 7.769×10-7 .The oxidation reaction is inhibited by competitive inhibition by kojic acid with IC50 = 200 μM and molecular modeling studies geometrical optimization ,(HOMOs) ,(LUMOs and electrostatic potentials (ESP).
Benzopyran derivative,Oxidation,trihydroxybenzene. biomimetic,metalloenzymes,Molecular
https://ejchem.journals.ekb.eg/article_94752.html
https://ejchem.journals.ekb.eg/article_94752_073210f35525ea9f644167b25b980c78.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Application of Bagasse Extract in Economic Nannochloropsisoculata Mass Production
5183
5192
EN
A.B.
El-Sayed
Algal Biotechnology Unit, National Research Centre, Egypt
abokhairnrc@gmail.com
Nashwa A.H.
Fetyan
0000-0001-7973-7299
Soils, Water and Environment Research Institute, Agricultural Research Center,Egypt.
dr_nashwa1967@yahoo.com
Fatma
Ibrahim
Department of Microbiology, Faculty of Agriculture, Cairo University, Egypt
fatmamohamedalhwary123@gmail.com
Sayed
A. Fayed
Department of Biochemistry, Faculty of Agriculture, Cairo University, Egypt
M.W.
Sadik
Department of Microbiology, Faculty of Agriculture, Cairo University, Egypt
mahmoudsadik63@gmail.com
10.21608/ejchem.2020.30459.2651
Algae were considered as an alternative source of food and a lot of biologically active ingredient. Beside, algae nutrition seems to be the most limiting factor concerning proper growth and economy cost. The main figure in this respect is carbon nutrition. The aim of the current work was to use bagasse for carbon nutrition of Nannochloropsis alga beside the selection of the proper concentration. <br /> Growth was performed using F2 growth medium for inoculum preparation and sub-culturing, while artificial growth medium was made and used to be mass culture of alga. The investigated parameters were dry weight, total chlorophyll and carotenoids.<br /> Results showed that a high nutritional composition of bagasse extract as an alternative source of organic carbon (89.9% of total cell carbon)and other nutrients0.035 N, 7.0 P and 51K .(ppm)especially when integrated with original growth medium (F2)and bagasse extract led to extra growth enhancement. Low and medium concentrations of bagasse in cultures free growth medium led to decrease the chlorophyll content and the maximum chlorophyll content (0.54g.l-1) was obtained by cultures grown with full F2 growth medium enriched by 10% of bagasse extract. By such ctreatment, carotene possessed the lowest (0.14g.l-1)outdoor zigzag shape photobioreactor led to the highest volumetric algal biomass production compare to indoor systems .Unit specification markedly affected growth characteristics and yield both of Nannochloropsisoculata in dry weight and oil content.Chemical composition reveledthe relatively high content of carbohydrates (26.6%) and oils (11.9%) on the expense of protein content (32.8%) and the maximum figure of ash content (2%) goes back to sodium ions.
Nannochloropsis oculata,Bagasse, Growth, Chemical composition
https://ejchem.journals.ekb.eg/article_103898.html
https://ejchem.journals.ekb.eg/article_103898_bc4a5e550a2140f74da98d17d72e0e3b.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Simple, Cheap and Low Waste System for Drinking Water Treatment Using Fabricated Polymeric Spiral Wound Ultrafiltration Modules
5193
5201
EN
Marwa S.
Shalaby
Chemical Engineering and Pilot Plant Department, Engineering Research Division, National Research Centre,
12311, Dokki, Giza, Egypt
Heba
Abdallaha
Chemical Engineering and Pilot Plant Department, Engineering Research Division, National Research Centre,
12311, Dokki, Giza, Egypt
Sayeda M.
Abdo
Water pollution Department, Environmental Pollution Research Division, National Research Centre,
12311, Dokki, Giza, Egypt,
Rehab
Mahmoud
Water pollution Department, Environmental Pollution Research Division, National Research Centre,
12311, Dokki, Giza, Egypt,
rehabhamdy02@gmail.com
A.M
Shaban
Water pollution Department, Environmental Pollution Research Division, National Research Centre,
12311, Dokki, Giza, Egypt,
10.21608/ejchem.2020.29610.2638
Simple, cheap and low waste system for drinking water treatment was designed and installed as a pilot system. Ultrafiltration polymeric membranes were prepared using polyvinylchloride and polyvinylidene difluoride. The membranes were prepared by phase inversion process and were characterized by scan electron microscope, mechanical testing and membrane performance test. Spiral wound polymeric membranes modules were fabricated and used in fabricated pilot system. Continuous tap water stream was used in this experiment for six months. The results indicated that PVC spiral wound membrane module provides high productivity 9.36 m3/d, with organic removal (COD) 100%, blue green algae removal 100%, 95.7% for total algae removal and clear bacteria from water efficiently. The results of this study affirm that none of the water quality parameters (chemical or biological) that were monitored in this study exceeded the Standard Specification for Egyptian Drinking Water.
Drinking water,Polyvinylchloride,polyvinylidene di fluoride,Spiral wound module
https://ejchem.journals.ekb.eg/article_97549.html
https://ejchem.journals.ekb.eg/article_97549_3a5f79fb9ce265fc3aaa7b1aa7188daa.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Design and Synthesis of Novel Pyrazoles, Pyrazolines, and Pyridines from Chalcone Derivatives with Evaluation of Their In Vitro Anticancer Activity Against T-47D and UACC-257 Cell Lines
5203
5218
EN
Mangoud
Mohamed
Mangoud
0000-0003-3032-3321
4 Ibn Khaldoun Square
mangoud_online@yahoo.com
Mohamed
Zaki
Hussein
Environmental Research Department, National Center for Social and Criminological Research,
Ibn Khaldoun Square, Mohandesin, Zamalek, Giza 11561, Egypt
mohamedzaki1955@yahoo.com
Eman
A.
El-Bordany
0000-0001-9224-4800
Department of Chemistry, Faculty of Science, Ain Shams University, Cairo 32511, Egypt
emanslime@yahoo.com
10.21608/ejchem.2020.28793.2620
Novel series of pyrazoline carbothioamides, acetyl pyrazoles, pyridine-3-carbonitriles, pyridine-2-carbonitriles, and nicotinonitriles were synthesized. The structures of the newly synthesized compounds were established based on their spectral data, elemental analyses and alternative synthetic routes whenever possible. Also, the newly synthesized compounds were screened for their in vitro anticancer activity against T-47D (breast cancer human cell line) and UACC-257 (melanoma human cell line) by MTT assay (a colorimetric assay for assessing cell metabolic activity). Experimental results demonstrated that compounds 3a, 4a, and 8c showed excellent in vitro activity against T-47D cell line, while compounds 3d, 6d, and 5b exhibited excellent activity against UACC-257 cell line. Molecular docking studies were performed on compound 4a, as it showed the most promising activity against T-47D cell line, using Molecular Operation Environment (MOE 2008.10) software. Also, drug-likeness, pharmacokinetics, and toxicity assessment studies were carried out.
Anticancer,docking,Pharmacokinetics,Chalcones,Pyrazolines,carbonitriles,cyanopyridines
https://ejchem.journals.ekb.eg/article_97553.html
https://ejchem.journals.ekb.eg/article_97553_fbeb80f81d8b84cf2d08b9e5b32adff4.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Evaluation of Uranium Adsorption Using Magnetic-Polyamine Chitosan from Sulfate Leach Liquor of Sela Ore Material, South Eastern Desert, Egypt
5219
5238
EN
Ahmad
Attallah
Tolba
0000-0003-0658-3553
Uranium ore processing department, Production sector, Nuclear Materials Authority, El-Maadi, Cairo, Egypt
ibn_ata@yahoo.com
10.21608/ejchem.2020.27972.2586
Chitosan particles with magnetic properties were prepared by co-precipitation method combined with hydrothermal treatment, then crosslinked with epichlorohydrin followed by grafting of triethylenetetramine. The obtained adsorbent material was characterized by means of FTIR and XRD and its adsorption properties towards uranyl ions were firstly investigated from synthetic solutions as a function of pH, contact time and initial uranium concentration using batch method and at room temperature. The maximum adsorption capacity was found to be158.43 mg/g at pH 4 and initial uranium concentration of 300 mg/l. Urea solution of 0.5 mol/l acidified with a few drops of sulfuric acid 0.2 mol/l can be efficiently used for uranium recovery and the adsorbent can be recycled for at least five successive cycles with limited decrease in adsorption performance. Subsequently, the application efficiency of the adsorbent material was evaluated by testing uranyl adsorption from sulfate leach liquor of Sela ore material after adaptation of leaching conditions. Uranium ore sample was subjected to acid conventional leaching through direct agitation with sulfuric acid and the relevant variables affecting leaching efficiency were optimized as 60 g/l sulfuric acid with liquid/solid weight ratio 3 at 45 °C for 90 minutes. Under these conditions, the leaching efficiency of uranium was 92%. Uranium adsorption capacity from sulfate leach liquor was found to be 132.98 mg/g at pH 4 and shaken time of 60 minutes with initial uranium concentration of 200 mg/l. This adsorption capacity represents only about 87% from the adsorption ability from synthetic solutions (152.86 mg/g) at the same conditions.
Magnetic-polyamine chitosan,acid leaching,Uranyl adsorption
https://ejchem.journals.ekb.eg/article_98291.html
https://ejchem.journals.ekb.eg/article_98291_5b7897ba8df72c21f2f010b170610574.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Study of Electrochemical Redox Reaction of CuSO4 Salt with Amoxicillin at Different Temperatures Using Glassy Carbon Electrode
5239
5249
EN
Mohamed
Fathi
Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt
mohamed.fathi257@yahoo.com
Shereen E.
Salem
Chemistry Department, Faculty of Science, Mansoura University, Mansoura, Egypt
Esam A.
Gomaa
Chemistry Department, Faculty of Science, Mansoura University, Mansoura, Egypt
Hamada M.
Killa
Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt
A.
Farouk
Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt
aya_sa92@yahoo.com
10.21608/ejchem.2020.24886.2477
The redox behavior of copper sulfate in absence and presence of Amoxicillin was studied at two different temperatures (288.15 and 298.15)K. The redox behavior was studied in 0.1 M HCl electrolyte, potential range from (1.5 to -1.5)V. The copper ions concentration is small ones ranging from (3.3×10-4 to 1.67×10-3)M. Only one reduction and one oxidation peaks are obtained in our results indicating the reduction and oxidation of the divalent copper ions to the zero valent copper metal. All the solvation cyclic voltammetry parameters were evaluated at the two temperatures used and their values were discussed for cupric ions in presence and absence of Amoxicillin. Also, the thermodynamic parameters for the interaction of copper ions with Amoxicillin as stability constant, Gibbs free energies, enthalpies and entropies of interaction were calculated. The thermodynamic parameters indicate that the reaction between cupric ions and Amoxicillin is chemical reaction (high negative Gibbs free energies values), good spontaneous (positive entropies) and endothermic chemical reaction (valuable positive values). Energy values of interaction between Amx and 2hg6 which obtained by molecular docking calculations indicate that Amx has an anticancer activity for liver cancer treatment
Redox reaction,Cyclic voltammetry,amoxicillin,CuSO4,Temperature,Thermodynamic parameters,Molecular docking
https://ejchem.journals.ekb.eg/article_78943.html
https://ejchem.journals.ekb.eg/article_78943_9b8a97adb2512d0a16b875c8d0bb9e1a.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
A Review on: Biocidal Activity of Some Chemical Structures and Their Role in Mitigation of Microbial Corrosion
5251
5267
EN
Ashraf
M
El-Shamy
0000-0003-3672-509X
Physical chemistry department
elshamy10@yahoo.com
10.21608/ejchem.2020.32160.2683
Microbial corrosion has developed a foremost problematic in the oil and gas industrial field. This problem is by reason of the continual usage of water swamping in promoting oil recovery. This water moistens the walls of oil pipelines. Microbial corrosion is also present in other industries such as nuclear power reactors and in most hydro-power applications. Increased corporate infrastructure also leads to increased microbial corrosion. Sulfate Reducing Bacteria (SRB) is considered as the main kind of bacterial which cause of pipeline corrosion. Because of microbial deterioration is not understood, until recently, there is no clear mechanism to explain why and how microbial corrosion occurs because of the complexity of this area. The new theory of bio-catalytic cathodic sulfate reduction is bio-electrochemistry based. In this theory, the bio-energetics can explain why microbial corrosion occurs, while the extracellular electron transference theory is capable of explain how microbial corrosion happens. The microbial corrosion can be caused by nitrate reducing bacteria, which led to an analogous bio-catalytic cathodic nitrate reduction theory. The electron mediator assessment intended to validate the extracellular electron transference progression which anticipated in bio-catalytic cathodic sulfate reduction. The electron mediators like riboflavin and flavin adenine di-nucleotide were accomplished of hastening the microbial corrosion by endorsing electron transport flanked by an iron surface and a biofilm. In case of deficient in organic carbon, the elemental iron substituted the organic carbons as an energy source/electron donor for SRB to get their conservation energy. Under unblemished undernourishment of organic carbon, the largest pit depth was accomplished, which was consistent with the estimate of bio-catalytic cathodic sulfate reduction. The developing request and crucial necessity in oil and gas industry is to find an effectual method to avoid and/or mitigate microbial corrosion at a rational cost.
Microbiological corrosion,Sulfate-reducing bacteria,Biocides enhancer
https://ejchem.journals.ekb.eg/article_105969.html
https://ejchem.journals.ekb.eg/article_105969_293be2211ebf1364b83eae35dc5b548c.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Selective Formula as A Corrosion Inhibitor to Protect the Surfaces of Antiquities Made of Leather-Composite Brass Alloy
5269
5287
EN
Mohamed
Moatamed
Megahed
El Fayom university
mmm03@fayoum.edu.eg
Mohamed
Youssif
Miser University of Science and Technology, 6th of October City, Egypt
youssefm419@yahoo.com
Ashraf
M
El-Shamy
0000-0003-3672-509X
Physical chemistry department
elshamy10@yahoo.com
10.21608/ejchem.2020.41575.2841
The interactions between the metal and the surroundings are responsible for electrochemical reactions that contribute to corrosion. To mitigate or deter corrosion of exposed metal in a corrosive environment, and corrosion agent must be applied to the metal surface to prevent further oxidation and therefore the presence of corrosion materials. One of the common techniques used by professionals associated in conservation-restoration to preserve metallic cultural heritage is the corrosion inhibitors. The second section of the thesis deals with the conservation and management by using an environmentally friendly corrosion agent of the corrosion of brass composite brass leather parts from the Bulaq Museum, Cairo, Egypt. Microscope Optical and scanning electron Analysis was performed to determine the microstructure of the alloy. Determining the alloy chemical composition of the identified objects using dispersive energy spectroscopy (EDS). Using X-ray diffraction (XRD), corrosion products were established. Finally, the effectiveness of composites between industrial corrosion inhibitors and surfactant materials was identified by the positive effects of (TTA + SLS) on handling. Before and after treatments the brass surfaces were described using SEM, EDS, XRD, FTIR, and XPS.
brass,conservation,coating,Electrochemical Characterization,Corrosion Control
https://ejchem.journals.ekb.eg/article_113697.html
https://ejchem.journals.ekb.eg/article_113697_8246c0bcf6452e58055b763ead8e32d8.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Sulfonamides: Synthesis and the recent applications in Medicinal Chemistry
5289
5327
EN
Mohamed
El-Gaby
0000-0002-4902-5546
Department of Chemistry, Faculty of Science, Al Azhar University, Assiut 71524, Egypt
m_elgaby@hotmail.com
Yousry
A. Ammar
Department of Chemistry, Faculty of Science, Al-Azhar University, Cairo
yossry@azhar.edu.eg
Mohamed
I. H. El-Qaliei
0000-0001-9624-0751
Department of Chemistry, Faculty of Science, Al-Azhar University at Assiut, Assiut
mohamedahmed.136@azhar.edu.eg
Ahmed
M. ali
Department of Chemistry, Faculty of Science, Al-Azhar University, assiut
ahmedshatat82@yahoo.com
Modather
F. Hussein
Department of Chemistry, Faculty of Science, Al-Azhar University , Assiut
modatherepri82@gmail.com
Faraghally
A. Faraghally
Department of Chemistry, Faculty of Science, Al-Azhar University , Assiut.
ahmedhemo87@yahoo.com
10.21608/ejchem.2020.33860.2707
This review spotlights sulfonamides from different sides, including history, structure-activity relationship, chemistry, methods of classification and up to date ways for their synthesis. Moreover, the review includes a discussion of the varied pharmacological effects of sulfonamides. Sulfonamides have a good range of pharmacological activities like oral diuretics (furosemide, indapamide, chlorthalidone, thiazides); anticancer (E7070), carbonic anhydrase (CA) inhibitors (CAIs) (acetazolamide, dichlorophenamide, dorzolamide and brinzolamide), antiepileptics (zonisamide and sulthiame), for rheumatoid arthritis (Sulfasalazine) antiviral (Darunavir) anti-inflammatory (celecoxib), antibacterial (Sulfadizine), as Ophthamologicals (Dorzolamide) anticonvulsant (Zonisamide) cycloxygenase 2 (COX2) inhibitors (valdecoxib). these days, novel pills are launched, like apricoxib and pazopanib, which additionally include this organization. The sulfonamides competitively inhibit vitamin Bc synthesis in micro-organisms and subsequently inhibit multiplication of bacteria but don't actively kill them. they need been used against most gram-positive and lots of gram-negative bacteria, also as some fungi.
sulfonamides. Medicinal Chemistry. Pharmacological activities. Micro,organisms
https://ejchem.journals.ekb.eg/article_107311.html
https://ejchem.journals.ekb.eg/article_107311_e6ca8cccadbfe5a51156657eccb2f19e.pdf
National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT
Egyptian Journal of Chemistry
0449-2285
2357-0245
63
12
2020
12
01
Erratum: Identification of Novel Polyphenolic Secondary Metabolites from Pistacia Atlantica Desf. and Demonstration of their Cytotoxicity and CCl4 induced Hepatotoxicity in Rat
117
130
EN
Sahar
Awad Allah
Hussein
0000-0002-6305-508X
Head of department of Phytochemistry and Plant Systematics,Division of Pharmaceutical Industries,National Research Center, El Buhouth st., Dokki
Dokki, Cairo, Egypt
drsahar90@yahoo.com
Amani M.D.
El-Mesallamy
Department of Chemistry, Faculty of Science, Zagazig University, Zagazig,
Egypt
Salma O.K.
Othman
Department of Chemistry, Faculty of Science, Sebha University, Sebha, Libya
Abd el-Mohsen M.
Soliman
Department of Therapeutic Chemistry; National Research Centre, Cairo, Egypt
10.21608/ejchem.2019.16297.1994
As of late a great deal of studies have been led to distinguish regular mixes for counteractive action of the advancement and repeat of malignant growths. The present investigation went for investigating the auxiliary metabolites substance of Pistacia atlantica Desf. (Anacardiaceae) leaves extracts and surveying their cytotoxic activity towards some malignant growth cell lines. In addition, the defensive impact of aqueous methanol and ethyl acetate extracts towards the CCl4 induced hepatotoxicity in rodents was explored. Novel components isolation was done utilizing customary chromatographic systems. The structures of the novel components were clarified dependent on the UV, NMR spectral data information alongside their mass-spectrometric investigations. <br /> The ethyl acetate extract of P. atlantica leaves contains a complicated mixture of phenolic acids and gallotannines, were elucidated for the first time from this plant , including polyphenolic acid; ellagic acid (1); 3,3’- dimethoxyellagicacid (2) and gallotannines, namely: 1,2,3,4,6-penta-O-galloyl-β-4C1-glucopyranose (3); 1,6-digalloylglucopyranose (4) ;1,3-digalloyl glucopyranose (5); 2,3-digalloyl-glucopyranose,nilocitin (6) ;2,3,6-trigalloylglucopyranose (7) and 2,3-di-O-galloyl-4,6-O-hexahydroxydiphenoyl-(/)-4C1-glucopyranose, (8) . <br /> The identification of isolated compounds by conventional methods, spectroscopic analysis, including 1D-NMR , 2D-NMR, ESIMS and HRESI mass as well. The search for novel, potentially biologically active extract becomes much more efficient after identification of all compounds in that mixture. <br /> In vitro cytotoxic activity of methanol and ethyl acetate extracts of Pistacia atlantica and resulted new compounds on four human cancer cell lines to be specific: Colorectal adenocarcinoma cell line (Caco-2 cell line), Prostate carcinoma cell line ( PC3 cell line), hepatocellular carcinoma (HEPG2), Caucasian bosom adenocarcinoma (MCF-7). SRB assay was used to measure the potential cytotoxicity. <br /> The ethyl acetate extract showed a higher cytotoxicity to Caco-2 cell line with IC50 = 3.38 µg/ml and PC3 cell line with IC50=14.3 µg/ml. Furthermore, the methanol extract was least cytotoxic to normal cell lines. The strong cytotoxic potential was observed in pure compound pentagalloyl glucopyranose (3) to all three cancer cell lines (HEPG2, Caco-2, MCF-7) , IC50 of HEPG2 value = 4.5 µg/ml. the IC50 for Caco-2 was 11 µg/ml. and MCF7, IC50=13.5 µg/ml. as well , in comparison with pure compounds (4,7,8). The growth inhibition of 50% (IC50) for each extract was calculated from the optical density of treated and untreated cells.
Keywords: Pistacia Atlantica Desf. (Anacardiaceae),Novel polyphenolic compounds,in vitro cytotoxic activity,CCl4,Hepatoprotective activity
https://ejchem.journals.ekb.eg/article_48295.html
https://ejchem.journals.ekb.eg/article_48295_77d085d4fa5f3b766b11af0f6bb4619e.pdf