Synthesis of Dibenzofuran Derivatives Possessing Anticancer Activities: A Review

Moustafa, Gaber Osman Mohamed; Al-Wasidi, Asma S.; Naglah, Ahmed M.; Refat, Moamen

doi:10.21608/ejchem.2020.21937.2310

Synthesis of Dibenzofuran Derivatives Possessing Anticancer Activities: A Review

Document Type : Review Articles

Authors

¹ El-Tahreer str 456

² Department of Chemistry, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia

³ Peptide Chemistry Department, Chemical Industries Research Division, National Research Centre, 12622- Dokki, Cairo, Egypt

⁴ Taif University

10.21608/ejchem.2020.21937.2310

Abstract

This review focuses on reports concerning the isolation and/or synthesis of dibenzofuran derivatives’ isolation and synthesis (whether one of them or both occurs simultaneously) existing naturally while exhibiting evident biological anticancer activity. While not a comprehensive approach to all relevant compounds, the review intends to demonstrate anticancer activity’s reach related to said compounds instead and the various natural origins and synthetic methods from which and by which the compounds are to be secluded and prepared. Compounds with reduced benzene rings, e.g., morphine as well as its derivatives, are omitted, same for compounds with aromaticity disrupted by alkylation, as with usnic acid.

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