2-Aroylbenzoic acid was allowed to react with hydrazine hydrate, hydroxyl amine and methylhydrazine to afford the corresponding 5,6,7,8-tetrachlorophthalazin-1-one. The antimicrobial effect of the phthalazin-1-one in the water of the swimming pool and river can be discussed. DFT based on quantum chemical computational of the new compounds were synthesized with the objective of studying their antimicrobial activity. The newly synthesized compounds were characterized on the basis of their spectral (1H-NMR, Mass spectrum, IR and Elementary analysis
Rizk, S. A., Youssef, M. F., & Mubarak, A. M. (2020). Synthesis, DFT and Antimicrobial Studies of 5,6,7,8- Tetrachloro Phthalazin-1-ol and 2,3-Benzoxazin-1(2H)-one Derivatives. Egyptian Journal of Chemistry, 63(5), 1767-1777. doi: 10.21608/ejchem.2019.16936.2036
MLA
Sameh A. Rizk; Mohamed Fathy Youssef; Ahmed M. Mubarak. "Synthesis, DFT and Antimicrobial Studies of 5,6,7,8- Tetrachloro Phthalazin-1-ol and 2,3-Benzoxazin-1(2H)-one Derivatives". Egyptian Journal of Chemistry, 63, 5, 2020, 1767-1777. doi: 10.21608/ejchem.2019.16936.2036
HARVARD
Rizk, S. A., Youssef, M. F., Mubarak, A. M. (2020). 'Synthesis, DFT and Antimicrobial Studies of 5,6,7,8- Tetrachloro Phthalazin-1-ol and 2,3-Benzoxazin-1(2H)-one Derivatives', Egyptian Journal of Chemistry, 63(5), pp. 1767-1777. doi: 10.21608/ejchem.2019.16936.2036
VANCOUVER
Rizk, S. A., Youssef, M. F., Mubarak, A. M. Synthesis, DFT and Antimicrobial Studies of 5,6,7,8- Tetrachloro Phthalazin-1-ol and 2,3-Benzoxazin-1(2H)-one Derivatives. Egyptian Journal of Chemistry, 2020; 63(5): 1767-1777. doi: 10.21608/ejchem.2019.16936.2036
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