Prevalence, virulence factors and antibiotic susceptibility of Candida infection in children

Document Type : Review Articles

Authors

1 Department of Botany and Microbiology, Faculty of Science, Cairo University

2 Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University

3 Department of Botany and Microbiology, Faculty of Science, Cairo University, 12613 Giza, Egypt.

4 Faculty of Science, Cairo University

Abstract

Many human infections, including mucosal and invasive candidiasis, can be brought on by Candida species, opportunistic fungal pathogens. An increasing issue in tertiary care institutions around the world is candidemia, the most notable form of invasive candidiasis. One of the most frequent reasons for bloodstream infections is Candida. Due to the extensive use of broad-spectrum antibiotics and immunosuppressive treatments, there has been a marked rise in the frequency of candidemia globally in recent years. Critically sick patients are put in danger by invasive candidiasis, a disorder with a high death rate that poses a serious health risk. The risk of death is higher for patients who are newborns, old, or admitted to intensive care units (ICUs). Over the past 20 years, there has been a marked rise in reports of Candida BSIs worldwide. Nosocomial BSIs caused by Candida are the sixth most frequent in Europe and the fourth most frequent in the United States. In this review, we discussed the different Candida infections and their mechanisms and also the association of Candida infections with the recent COVID-19 pandemic.

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Egyptian Journal of Chemistry
Volume 66, Issue 13 - Serial Number 13
Special Issue: Applied Chemistry for Greener Life and Sustainability
December 2023
Pages 2081-2099

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History

  • Receive Date: 02 August 2023
  • Revise Date: 28 August 2023
  • Accept Date: 03 September 2023

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