Synthesis and Evaluation of Some Amine Oxide Surfactants and Their Antimicrobial Activity

Abdel-Halim, Nermeen Mahmoud; Soliman, Elsayed Ahmed; El Dib, Fawzia Isamiel; Mohamed, Ammona Salem; Mohamed, Dalia Emam

doi:10.21608/ejchem.2023.217783.8173

Synthesis and Evaluation of Some Amine Oxide Surfactants and Their Antimicrobial Activity

Document Type : Original Article

Authors

¹ Petrochemicals Department, Egyptian Petroleum Research Institute, Cairo, Egypt.

² Chemistery, Faculty of Science, Ain shams university, Cairo, Egypt

³ Petrochemicals Department- Egyptian Petroleum Research Institute- Cairo- Egypt.

10.21608/ejchem.2023.217783.8173

Abstract

A series of three amine oxide-based surfactants were synthesized by esterification of diethanolamine with different fatty acids (octanoic, dodecanoic and hexadecanoic). The obtained esters of diethanol amine were alkylated with (1, 10) Dibromodecane and the products were oxidized with hydrogen peroxide to produce amine oxide surfactants. The chemical structures of these surfactants were confirmed using FTIR and 1H-NMR spectra. Also, the surface activity of the synthesized amine oxide surfactants has been studied including critical micelle concentration (CMC), effectiveness, efficiency, maximum surface excess and minimum surface area. The synthesized amine oxide surfactants were also evaluated as antimicrobial agents against different strains of bacteria including Gram-positive, Gram-negative, and fungi.

Keywords