Characterization and biological effectiveness of synthesized complexes of Palladium (II) from imine compounds

Hafidh, Shaimaa Hammad; Muslim, Rasim Farraj; Awad, Mohammed Ahmed

doi:10.21608/ejchem.2021.79085.3876

Characterization and biological effectiveness of synthesized complexes of Palladium (II) from imine compounds

Document Type : Original Article

Authors

¹ Department of chemistry, college of education for pure sciences, University Of Anbar, Anbar, Iraq

² Department of environmental, college of applied sciences-Hit, University Of Anbar, Anbar, Iraq

10.21608/ejchem.2021.79085.3876

Abstract

Abstract
This article involved synthesizing of novel Palladium (II) complexes as follows:
The imine compounds were prepared by reacting of aldehydes with the following nitrogen compounds: 4-methylbenzene-1,2-diamine, naphthalene-1,8-diamine, and 4-chloro-5-methyl benzene -1,2-di amine and sublimated into ethanol. The reaction was continued by thin layer chromatography (TLC), the imine compounds were determined by spectrophotometry of FT-IR UV-Visible, 1H-NMR.
The palladium complexes were synthesizing from the reaction of the prepared imine compounds after they were dissolved using ethanol and palladium salt (PdCl2), which was dissolved by using absolute ethanol with 4 drops of 11.6 N of HCl acid and the mixture was raised for 3 hours, when the amine compounds reacted with the Palladium ion (II), this interaction leads to the formation of palladium complexes, the reaction was continued by thin layer chromatography (TLC), the complexes were spectrophotometrically characterized by measuring ultraviolet-visible and infrared rays, mass spectrometry, molar conductivity measurement. An important role in knowing the geometric shape of the complexes has proven that the palladium complexes have a square planer shape.
Two types of bacteria were used, namely (Gram-Positive and Gram-Negative), and these types are: Staphylococcuus Aureus (Gram-Positive) and Escherichia coli (Gram-negative). Where they were chosen because they cause a number of diseases and both have a different nature of resistance to antibiotics and pharmaceuticals, as a number of prepared palladium complexes were selected to measure their effectiveness on these types of bacteria using the diffusion method. The results were good for some concentrations.
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