Pathogenic Effects of Ethion Residues and the Expected Protective Role of the Ethanolic Extract of Rosemary (Rosmarinus Officinalis L.) Leaves in Male Rats

Abdel-Gawad, Hassan; Soliman, Soliman; Taha, Hamdy; Aly, Mohamed; A. Abd El Kader, Monira; Hegazi, Bahira

doi:10.21608/ejchem.2021.59950.3282

Pathogenic Effects of Ethion Residues and the Expected Protective Role of the Ethanolic Extract of Rosemary (Rosmarinus Officinalis L.) Leaves in Male Rats

Document Type : Original Article

Authors

¹ Applied Organic Chem., Pesticides, NRC

² Applied Organic Chemistry Department, Chemical Industries Research Division, National Research Centre, 33 EL Buhouth St., Dokki, Giza, 12622, Egypt

³ Applied organic chemistry N R C

⁴ Department of Animal Reproduction and Artificial Insemination, Veterinary Research Division, National Research Centre, National Research Centre, Egypt

⁵ 3Biochemistry Department, Genetic Engineering and Biotechnology Division, National Research Centre, National Research Centre, Egypt

10.21608/ejchem.2021.59950.3282

Abstract

Organophosphate insecticides (OPI) poisoning remains a major cause of morbidity and mortality in the third world countries. The continuous use of these pesticides tends to leave residues of these pesticides in agricultural crops, which in turn may harm people. The present study aimed to investigate the pathogenic effects of the "ethion" residues and the expected protective role of the ethanolic extract of rosemary (Rosmarinus officinalis L.) (EER), in adult male rats. Feeding animals with Maize containing ethion residues (4 mg/Kg) caused elevation in serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) activities (P

Keywords