Synthesis of New Heterocycles Incorporating 3-(N-phthalimidomethyl)-1,2,4-triazole as Antimicrobial Agents

Abstract

          NOVEL series of 1,2,4-triazole Schiff’s bases;1,2,4-……..triazolothiadiazinesand triazolothiadiazoles was prepared from reaction of 4-amino-3-(N-phthalimidomethyl)-1,2,4-triazole-5-thione and different aldehydes, hydrazonyl chlorides, 𝛼-haloketones, and substituted benzoic acids. The products have been evaluated for their antimicrobial activity and the Schiff’s bases were found to exhibit an antimicrobial activity.
 
 

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