Solid Phase Synthesis of I25 Labeled Insulin Fragments. Part III. Synthesis of 125-I-Insulin Fragment B15-18 Leu-Tyr(I2)-Leu-Val

Abstract

 
NOWA DAYS, synthesis of biological active peptides has been found in an impressive success. This has been achieved by development of new techniques, using new reagents and easy reach.
A new approach to radio-peptides synthesis has been investigated in an effort to overcome the technical difficulties of separation, purification and identification of the prepared peptide fragments. In a series of solid-phase peptide synthesis of labeled insulin fragments, we have prepared 125-I-Insulin fragment Bl 5-18. In this research work we discussed the synthesis of Insulin fragment B15-18 Labeled with Leu-Tyr(I
2 )-Leu-Val.

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