Fabrication and Characterization of Nano-Hydroxyapatite\ Chitosan Biocomposites with and without Citric Acid Addition

Abstract

 
BIOCOMPOSITES composed of carbonated apatite and chitosan in ….. the presence or absence of citric acid were fabricated through a co-precipitation method. The prepared biocomposites were characterized by Fourier transformed infrared spectroscopy (FT-IR), X- ray diffraction (XRD), Thermo gravimetric analysis (TGA), Transmission electron microscopy (TEM), and Scanning electron microscopy (SEM). The results proved that the presence of citric acid in the composite accelerated HA formation and reduced its particle size. Also, the compressive strength increased for HA/chitosan composite compared to HA alone and more increased with addition of citric acid which enhanced the binding strength between HA particles. The HA/chitosan composite with ratio 70% HA and 30% chitosan, especially with citric acid, may be promising for bone grafting and bone tissue engineering applications.

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