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SIMPLE, rapid and sensitive spectrophotometric method was developed for the determination of gemifloxacin mesylate (GMF), moxifloxacin.HCl (MXF) and gatifloxacin sesquihydrate (GAF) in pure and pharmaceutical preparation. This method is based on ion pair formation reaction between GMF, MXF and GAF and rosebengal indicator in universal buffer of pH 5.The formed ion pair is measured at λmax = 575 nm. All optimum conditions are established. The calibration graphs are rectilinear at concentration ranges 9.71 – 53.40, 8.758 – 52.55 and 8.048– 48.29 μg ml-1 for GMF, MXF and GAF, respectively. The sandell sensitivity (S) = 0.0263 , 0.0244 and 0.0263 μg cm-2 , molar absorptivity = 1.861x 104 , 1.835x 104 and 1.561x 104 L mol-1 cm-1 , correlation coefficient 0.9998 and LOD = 01.90, 1.607 and 1.876 μg ml-1 and LOQ = 05.74, 0.2036 and 5.684 μg ml-1 are calculated for GMF, MXF and GAF, respectively. The values of SD are = 0.0218 - 0.0297, 0.02 - 0.0377 and 0.0216 - 0.0282 and RSD are = 0.0554 - 0.3075, 0.0380 - 0.4344 and 0.0537 - 0.3497 % for GMF, MXF and GAF. The method is applied for the assay of investigated three drugs in pharmaceutical dosage forms. The results are in good agreement with those obtained by the official methods
THE number of efforts in order to modify the properties ofpolymeric fibers by organic or inorganic particles has increasedin recent times because of increasing interest of fiber research inhightech fiber applications. In addition to these attempts, theinnovation of nanotechnology also leads to the development ofnanoparticles for various end uses such as nanocomposite fibers. Inthis study Calcium oxide nanoparticles (CaO) were introduced intopolyamide 6 (PA6) and drawn into filaments through a melt extrusionprocess. The effect of CaO nanoparticles on the thermal, structural,morphological and tensile properties of polyamide-CaOnanocomposites fibers was investigated by using thermal gravimetricanalysis (TGA), X-ray diffraction (XRD), Fourier transform infraredspectroscopy (FTIR), scanning electron microscopy (SEM) andmechanical properties, respectively.