@article { author = {}, title = {Sythesis of Some New Quinazolin-4-one Derivatives}, journal = {Egyptian Journal of Chemistry}, volume = {54}, number = {4}, pages = {411-422}, year = {2011}, publisher = {National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT}, issn = {0449-2285}, eissn = {2357-0245}, doi = {10.21608/ejchem.2011.1402}, abstract = { TREATMENT of 3,4-dihydroquinazolin-4-one (2a) with P2S5 ……..yielded the corresponding thione 3 that treated with hydrazine/or 2-aminoethanol afforded quinazoline derivatives 4.The hydrazinoquinazoline 4b converted to (sulphahydryl and/or methyl) triazoloquinazoline via interaction with CS2 and Ac2O. On the other hand, compound 2a reacts with ethyl chloroacetate yielded the ester derivative 9 which converted to the corresponding hydrazide 10 via interaction with hydrazine hydrate. Its behavior of hydrazide 10 towards carbon electrophiles, e.g., thiophene-2-carboxaldehyde, furfural, piperonal, o-anisaldehyde, phthalic anhydride, ammonium thiocyanate, acetyl acetone, Ac2O and ethyl acetoacetate afforded compounds 11-16. Also, behavior of compound 2b towards carbon electrophiles, e.g. acetic anhydride and benzoyl chloride afforded 17. A moderate activity was observed with new quinazolinone compounds 4-10 which proved to possess marked activity against E. coli, S. aureus and C. albicans. The strong activity was observed with compounds 3,11-17.}, keywords = {(3H) quinazolin 4one,1,3,4 Oxadiazolequinazolinone,Phthali-mido,Furan,THIOPHENE,Pyrazoloquinazoline and 1,2,4-Triazole quinazoline}, url = {https://ejchem.journals.ekb.eg/article_1402.html}, eprint = {https://ejchem.journals.ekb.eg/article_1402_faaa69718230716437e6f9b4e3d52aba.pdf} } @article { author = {}, title = {New Access to Indenopyridine, Indenothiophene, Indenoisoxazole, Indenopyrazole, 2,2-Bis (2,5-dihydroxyphenyl)indane-1,3-dione and Indane-1-one Derivatives}, journal = {Egyptian Journal of Chemistry}, volume = {54}, number = {4}, pages = {423-438}, year = {2011}, publisher = {National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT}, issn = {0449-2285}, eissn = {2357-0245}, doi = {10.21608/ejchem.2011.1403}, abstract = {SEVERAL new indenopyridine, indenothiophene, indenoisoxazole ,indenopyrazole, 2,2-bis (2,5-dihydroxyphenyl) indane-1,3-dione and indane-1-one derivatives which have a biological usage as potential biodegradable agrochemicals, and blood anticoagulants were prepared from cyclic ketones (1a-d) and active methylene nitriles (2a,b) as starting components.}, keywords = {}, url = {https://ejchem.journals.ekb.eg/article_1403.html}, eprint = {https://ejchem.journals.ekb.eg/article_1403_bfd01b3eccf1e4de864877f7cb9a7c89.pdf} } @article { author = {}, title = {Surface Active Rubidium Carbonate Obtained from The Thermal Decomposition Course of Rubidium Acetate}, journal = {Egyptian Journal of Chemistry}, volume = {54}, number = {4}, pages = {455-467}, year = {2011}, publisher = {National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT}, issn = {0449-2285}, eissn = {2357-0245}, doi = {10.21608/ejchem.2011.1404}, abstract = { THE THERMAL decomposition course of rubidium acetate ……. Rb(CH3COO) was probed on heating up to 1000 °C in a dynamic atmosphere of air by thermogravimetry and differential thermal analysis. The solid and gas-phase decomposition products were identified by X-ray diffractometry, ex- and in-situ infrared spectroscopy and mass spectrometry. Results obtained showed the acetate to decompose stepwise to yield eventually Rb2O at ≥ 900 °C encompassing the formation of the intermediate Rb2CO3 solid product (at 400-700 °C)) and H2O, (CH3)2CO and CO2 as primary gaseous products. A considerable enhancement of the production of primary gas phase products at 400-450 °C and the emergence of (CH3)2C=CH2, CH4 and CO molecules in the gas phase are ascribed to reactions occurring at the gas/solid interface at the expense of some of the primary products. The activity at the gas solid interface has been indicated These interfacial activities impart application-worthy adsorptive and catalytic functions for the associated solid products.}, keywords = {Rubidium acetate,Rubidium carbonate,Infrared spectroscopy,Thermal analysis and Gas/solid interfacial reactivity}, url = {https://ejchem.journals.ekb.eg/article_1404.html}, eprint = {https://ejchem.journals.ekb.eg/article_1404_084da7924857d1aed8c0b23e522eafd3.pdf} } @article { author = {}, title = {Cyclopalladate Complexes of 4-Methoxy-N- {(E)-(piperidin-1-yl) phenyl) Methylene} Aniline: Synthesis, Spectral Characterization and Biological Evaluation}, journal = {Egyptian Journal of Chemistry}, volume = {54}, number = {4}, pages = {469-480}, year = {2011}, publisher = {National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT}, issn = {0449-2285}, eissn = {2357-0245}, doi = {10.21608/ejchem.2011.1405}, abstract = {THE REACTION of palladium acetate with 4-Methoxy-N-{(E)-(piperidin-1-yl)phenyl) methylidene}aniline (L) gave the cyclometallated acetate bridged complex (1) with open book-shape structure. Metathetical reaction of (1) with NaCl, NaBr and NaI gave the corresponding halidobridged complexes (2), (3) and (4), respectively. Monomerization of complex (3) with pyridine gave compound (5). The ligand and complexes have been characterized by IR, 1H NMR, U.V-Vis and Mass Spectroscopy as well as by magnetic susceptibility measurements. Antimicrobial screening of the ligand and complexes showed that the acetate bridged complex (1) has higher activity than other compounds.}, keywords = {Cyclopalladation,complexes,Synthesis and Biolgical activity}, url = {https://ejchem.journals.ekb.eg/article_1405.html}, eprint = {https://ejchem.journals.ekb.eg/article_1405_0908642be43bcdb825dd1646b1b0ea7d.pdf} } @article { author = {}, title = {A Novel Application of Ionic Liquid in Improvement of The Felting Resistance of Wool}, journal = {Egyptian Journal of Chemistry}, volume = {54}, number = {4}, pages = {481-493}, year = {2011}, publisher = {National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT}, issn = {0449-2285}, eissn = {2357-0245}, doi = {10.21608/ejchem.2011.1406}, abstract = { THE EFFECT of treatment of wool using two different ionic ……liquids namely 1-ethyl -3-methyl imidazolium acetate (EMIA), and 1-butyl -3-methyl imidazolium chloride (BMIC), on the felting resistance of wool was studied. The effect of treatment temperature and treatment time on the yellowing index, tenacity, and elongation at break of the treated wool fibres, was examined. Elemental analysis elucidated a remarkable reduction in sulphur content of the treated wool, which is mainly present in the wool scales. Scanning electron microscopy confirmed partial removal of wool scales under the effect of ionic liquid.}, keywords = {Wool fibre,Ionic liquid,Imidazolium salts and Anti-felting}, url = {https://ejchem.journals.ekb.eg/article_1406.html}, eprint = {https://ejchem.journals.ekb.eg/article_1406_e12c8356147431cffdcb1b63f3a891fd.pdf} } @article { author = {}, title = {An Approach to Impart Bactericidal Effect to Viscose Fabric Using Ionic Liquids}, journal = {Egyptian Journal of Chemistry}, volume = {54}, number = {4}, pages = {495-507}, year = {2011}, publisher = {National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT}, issn = {0449-2285}, eissn = {2357-0245}, doi = {10.21608/ejchem.2011.1407}, abstract = { THE ANIONIC agent (AA) dichloro triazinyl amino benzene .........sulphonate was prepared and applied to viscose fabrics. The pretreated fabrics were then treated with selected ionic liquids (ILs); namely 1-butyl 3-methyl imidazolium bromide (BMIB), 1-butyl 3-methyl imidazolium chloride (BMIC), 1-ethyl 3-methyl imidazolium acetate (EMIA) and 1-ethyl 3-methyl imidazolium ethyl sulphate (EMIES). Viscose fabrics treated with AA/IL system has shown excellent bacterial resistance to gram +ve and gram –ve bacteria when properly treated with the selected ionic liquid. The substantivity of the cationic agent to viscose fabric and hence the bactericidal effect, increase in the order BMIB>BMIC>EMIES>EMIA. Marvelous durability of the treated fabrics was observed after 10 washing cycles of the treated fabrics. Infrared spectroscopy as well as nitrogen content of the untreated as well as treated viscose fabrics was conducted to ensure strong and permanent fixation of both the anionic agent and the ionic liquids to the viscose fabrics.}, keywords = {viscose,ionic liquids,Antibacterial,Triazine and Imidazolium}, url = {https://ejchem.journals.ekb.eg/article_1407.html}, eprint = {https://ejchem.journals.ekb.eg/article_1407_eae3d330a4aa785ee8a0d3906e67f6a9.pdf} } @article { author = {}, title = {New Pyridone, Furopyridine and Pyrazolo-pyridine Derivatives Bearing 5,6,7,8-Tetrahy-dronaphthalene Moiety: Synthesis, Antimicrobial and Genotoxicity Evaluation}, journal = {Egyptian Journal of Chemistry}, volume = {54}, number = {4}, pages = {509-532}, year = {2011}, publisher = {National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT}, issn = {0449-2285}, eissn = {2357-0245}, doi = {10.21608/ejchem.2011.1408}, abstract = {REACTIONof 2-acetyl-5,6,7,8-tetrahydronaphthalene (1) with different aromatic aldehydes yielded the corresponding cyanopyridone derivatives 2a,b. Upon heating of 2a with chloroacetone, led to the formation of furopyridine derivative 4, while the reaction of compounds 2a,b with ethyl bromoacetate afforded 3–cyanopyridinyl derivatives 5a, b. Condensation of 5a,b with different amines gave the compounds 6a, b, 7 or 8a, b, respectively. Pyrazolopyridine derivatives 9a, b, 10a, b, 11 were obtained upon the reaction of compound 8a with different aromatic aldehydes, ketones and/or substituted malononitrile. The antimicrobial activity evaluation exhibited that 7, 10a,b are promising antibacterial and antifungal agents. Genotoxicity evaluation indicated that both 2a, 8a produced a protection against cytogenetic changes induced by cyclophosphamide in mice.}, keywords = {pyridone,Furopyridine,Pyridine,Pyrazolopyridine and Genotoxicity}, url = {https://ejchem.journals.ekb.eg/article_1408.html}, eprint = {https://ejchem.journals.ekb.eg/article_1408_b3e78abd325d22ed0c9a7a17f97461fc.pdf} } @article { author = {}, title = {Synthesis, Characterization and Stability of the Polymeric Complexes of Zinc (II), Cadmium (II) and Cerium (III) with 1,4-bis (2`-carboxyphenyla-zomethine) phenylene}, journal = {Egyptian Journal of Chemistry}, volume = {54}, number = {4}, pages = {533-548}, year = {2011}, publisher = {National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT}, issn = {0449-2285}, eissn = {2357-0245}, doi = {10.21608/ejchem.2011.1409}, abstract = {THE FORMATION and stability of binary Zn 2+, Cd2+ and Ce3+ complexes with 1,4-bis(2`-carboxyphenylazomethine)phenylene (BCPAP) were studied by potentiometric pH-titrations in 50% (v/v) 1,4 dioxane-water medium [I=0.1M KNO 3], 25°C. Under uniform conditions the dissociation constants of the ligand BCPAP have also been examined. The potentiometric data showed that the metal contents in all complexes are consistent with 1:1 metal: ligand stoichiometry. From the formation curves the stepwise stability constants of binary chelates were determined and the optimal pH conditions for preparing the solid complexes were specified. The synthesized complexes were characterized using elemental analysis, infrared and electronic spectra. The reaction of the bis–bidentate ligand (1,4-bis (2`-carboxyphenylazomethine)phenylene) BCPAP with each of Zn2+, Cd2+ and Ce3+ gives coordination polymers. Thermal stabilities of the various coordination polymers were studied. The isolated coordination polymers were investigated by differential scanning calorimetry (DSC) to determine the glass transition temperature (Tg). The obtained Tg and DSC data, showed the formation of one kind of coordination polymers (homo-coordination polymers). The conductivity of the polychelates were measured both from the solution and electrode side. The surfaces of the samples were examined by scanning electron microscopy (SEM).}, keywords = {Polychelates,zinc,Cadmium and cerium,Schiff base,Synthesis,Characterization,Potentiometric study and SEM}, url = {https://ejchem.journals.ekb.eg/article_1409.html}, eprint = {https://ejchem.journals.ekb.eg/article_1409_afdef288294638664bb41841ed0dbaaa.pdf} } @article { author = {}, title = {Synthesis, Stability, Spectral and Characterization of Mercury (II) Complexes with a Novel Bis-Schiff base Ligand}, journal = {Egyptian Journal of Chemistry}, volume = {54}, number = {4}, pages = {549-563}, year = {2011}, publisher = {National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT}, issn = {0449-2285}, eissn = {2357-0245}, doi = {10.21608/ejchem.2011.1410}, abstract = { ANEW reagent, (2E,2'Z) -2,2'- (3- ((E)- (2-hydroxyphenyl) ..........diazenyl) pentane-2,4- diylidene) bis (hydrazinecarbothio-amide) (OPTS) was synthesized and studied. Acid-base, spectrophotometric properties of OPTS were studied in 50% ethanol-water mixture solutions at pH 3–11. Dissociation constants of the reagent OPTS have been determined by spectrophotometry and potentiometric titrations: pK1=9.60±0.02; pK2=10.45±0.05 in its computational and graphical versions at an ionic strength 0.1M. The stability constants of the Hg-OPTS are logK1=6.18±0.04 and logK2=5.22±0.05. The reaction of Hg(II) with OPTS gives mononuclear complex in 50% ethanol - water mixture solution with λmax = 448 nm at pH 8.5. The effects of foreign ions and masking agents on the determination of Hg(II) with the new reagent were monitored. The mono complex obey the Beer law in the Hg(II) concentration range 5.10–50.17 mg/25ml. Molar absorption coefficients was determined. In this paper, we report the synthesis of the novel Hg(II) complexes with OPTS. The complexes were characterized by UV-vis and IR spectroscopy, elemental analysis, molar conductivity and thermal decomposition.}, keywords = {Mercury (II) complexes,Bis (thiosemicarbazone),Synthesis,Physico-chemical characterization and Thermal decomposition}, url = {https://ejchem.journals.ekb.eg/article_1410.html}, eprint = {https://ejchem.journals.ekb.eg/article_1410_6d69221165b003cc9a145d7aee9004ff.pdf} } @article { author = {}, title = {Synthesis and Tranquillizing Effect of New 1,4-Benzoxazepines}, journal = {Egyptian Journal of Chemistry}, volume = {54}, number = {4}, pages = {565-578}, year = {2011}, publisher = {National Information and Documentation Centre (NIDOC), Academy of Scientific Research and Technology, ASRT}, issn = {0449-2285}, eissn = {2357-0245}, doi = {10.21608/ejchem.2011.1411}, abstract = { SAERIES of new 1,4-benzoxazepin-5(4H)-ones was prepared by …….alkylation of salicylamides with phenacyl bromides followed by cyclodehydration of the resulting amides. Treatment of the 1,4-benzoxazepine-5(4H)-ones with phosphorus pentasulphide afforded the corresponding 1,4-benzoxazepine-5(4H)-thiones. N-alkylation of the 1,4- benzoxazepin-5(4H)-ones and S-alkylation of the 1,4-benzoxazepine-5(4H)-thiones were described. Some of the new compounds were subjected to preliminary screening for their tranquilizing effect.}, keywords = {4-Benzoxazepin-5(4H)-ones,1,4-Benzoxazepine-5(4H)-thiones,N-alkylation,S- alkylation,Tranquilizers and Diazepam}, url = {https://ejchem.journals.ekb.eg/article_1411.html}, eprint = {https://ejchem.journals.ekb.eg/article_1411_7871f498f219a076ea35d803b6afdccb.pdf} }